(S)-4-benzyl-3-allyloxazolidin-2-one

Base Information

• Chemical Name: (S)-4-benzyl-3-allyloxazolidin-2-one
• CAS No.: 1263814-86-3
• Molecular Formula: C₁₃H₁₅NO₂
• Molecular Weight: 217.268
• Mol file: 1263814-86-3.mol

Synonyms:(S)-4-benzyl-3-allyloxazolidin-2-one

Chemical Property of (S)-4-benzyl-3-allyloxazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (S)-4-benzyl-3-allyloxazolidin-2-one

There total 1 articles about (S)-4-benzyl-3-allyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(S)-4-Benzyl-2-oxazolidinone (90719-32-7) + allyl bromide (106-95-6) → (S)-4-benzyl-3-allyloxazolidin-2-one (1263814-86-3)

Guidance literature:

(S)-4-Benzyl-2-oxazolidinone; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.166667h; Inert atmosphere; Schlenk technique;

allyl bromide; In tetrahydrofuran; mineral oil; at 0 - 25 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.202004946

Reference yield: 45.0%

(S)-4-benzyl-3-allyloxazolidin-2-one (1263814-86-3) + butyraldehyde (123-72-8) → (S)-4-benzyl-3-(4-oxoheptyl)oxazolidin-2-one

Guidance literature:

With benzophenone; N-hydroxyphthalimide; at 25 ℃; for 45h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1002/chem.202004946

Reference yield:

carbon monoxide (201230-82-2) + (S)-4-benzyl-3-allyloxazolidin-2-one (1263814-86-3) + 1-(3,5-bis((piperazin-1-yl)methyl)benzyl)piperazine (944408-70-2) → C63H87N9O6 (1287665-52-4) + C63H87N9O6 (1207868-49-2)

Guidance literature:

carbon monoxide; (S)-4-benzyl-3-allyloxazolidin-2-one; With (acetylacetonato)dicarbonylrhodium (l); hydrogen; 6,6′-[(3,3′-di-tert-butyl-5,5′-dimethoxy-1,1′-biphenyl-2,2′-diyl)bis(oxy)]bis(di-benzo[d,f][1,3,2]dioxaphosphepin); In 1,4-dioxane; at 50 ℃; for 48h; under 7500.75 Torr;

1-(3,5-bis((piperazin-1-yl)methyl)benzyl)piperazine; In 1,4-dioxane; at 100 ℃; for 48h; under 30003 Torr;

DOI:10.1002/adsc.200900267

upstream raw materials:

(S)-4-Benzyl-2-oxazolidinone

allyl bromide

Downstream raw materials:

C₃₂H₄₄N₄O₄

C₃₂H₄₄N₄O₄

C₆₃H₈₇N₉O₆

C₆₃H₈₇N₉O₆

Refernces