2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

Base Information

Chemical Name:2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate
CAS No.:869060-07-1
Molecular Formula:C₂HF₃O₂*C₁₇H₁₈N₂O
Molecular Weight:380.367
Hs Code.:

Synonyms:2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

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Chemical Property of 2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

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Technology Process of 2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

There total 1 articles about 2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 869059-97-2
2,3-dihydro-2-[[(2-phenylethyl)amino]carbonyl]-(2S)-1H-indole-1-carboxylic acid 1,1-dimethyl ethyl ester

: 869060-07-1
2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h;

Reference yield: 49.0%

: 15084-51-2
4-tert-butylbenzenesulfonyl chloride

: 869060-07-1
2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate

: 1-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2,3-dihydro-N-(2-phenyl-ethyl)-(2S)-1H-indole-2-carboxamide

Guidance literature:: 2,3-dihydro-N-(2-phenylethyl)-(2S)-1H-indole-2-carboxamide trifluoroacetate; With IRA₄₀₀ resin; In dichloromethane; at 20 ℃; for 3h;

4-tert-butylbenzenesulfonyl chloride; With morpholine resin; In dichloromethane; at 20 ℃; for 16h;