(3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE

Base Information

Chemical Name:(3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE
CAS No.:28094-73-7
Molecular Formula:C₁₄H₁₇N₃O₃
Molecular Weight:275.307
Hs Code.:
Mol file:28094-73-7.mol

Synonyms:Carbamicacid, (3-diazo-1-isopropylacetonyl)-, benzyl ester (8CI)

Suppliers and Price of (3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE 95.00%
5MG
$ 499.33

Total 3 raw suppliers

Chemical Property of (3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE

Chemical Property:

PSA：92.79000
LogP:2.27906

Purity/Quality:

98% ^*data from raw suppliers

(3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE

There total 12 articles about (3S)-3-Z-AMINO-1-DIAZO-4-METHYL-2-PENTANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 90105-46-7,28094-73-7
benzyl (S)-(1-diazo-4-methyl-2-oxopentan-3-yl)carbamate

Guidance literature:: (S)-N-(benzyloxycarbonyl)valine; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; diethyl ether; at -25 ℃; for 0.5h;

diazomethane; In tetrahydrofuran; diethyl ether; at -10 - 20 ℃; for 3h;
DOI:10.1016/j.tetasy.2005.01.049

Reference yield: 75.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 1685-33-2
N-[(benzyloxy)carbonyl]-D-valine

: 28094-73-7
1-diazo-2-oxo-(3R)-3-benzyloxycarbonylamino-4-methylpentane

Guidance literature:: N-[(benzyloxy)carbonyl]-D-valine; With triethylamine; isobutyl chloroformate; In tetrahydrofuran; diethyl ether; at -20 ℃; for 0.5h; Inert atmosphere;

diazomethane; In tetrahydrofuran; diethyl ether; at -10 - 20 ℃; for 3.5h; Inert atmosphere;
DOI:10.14233/ajchem.2013.14080

Reference yield: 34.0%

: 1685-33-2
N-[(benzyloxy)carbonyl]-D-valine

: 18107-18-1
diazomethyl-trimethyl-silane

: 28094-73-7
1-diazo-2-oxo-(3R)-3-benzyloxycarbonylamino-4-methylpentane

Guidance literature:: N-[(benzyloxy)carbonyl]-D-valine; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at -15 ℃; for 0.5h; Inert atmosphere;

diazomethyl-trimethyl-silane; In hexane; acetonitrile; at 0 - 20 ℃; for 18h; Inert atmosphere;
DOI:10.1021/np100877h