6-Quinoxalinecarbonitrile

Base Information

• Chemical Name: 6-Quinoxalinecarbonitrile
• CAS No.: 23088-24-6
• Molecular Formula: C9H5 N3
• Molecular Weight: 155.159
• Hs Code.: 2933990090
• Mol file: 23088-24-6.mol

Synonyms:6-Cyanoquinoxaline

Chemical Property of 6-Quinoxalinecarbonitrile

Chemical Property:

• Melting Point: 176-178 °C
• Boiling Point: 329.7±22.0 °C(Predicted)
• PKA: -0.94±0.30(Predicted)
• PSA: 49.57000
• Density: 1.29±0.1 g/cm3(Predicted)
• LogP: 1.50148

Purity/Quality:

NLT 98% ^*data from raw suppliers

6-Quinoxalinecarbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Quinoxalinecarbonitrile

There total 3 articles about 6-Quinoxalinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

quinoxaline-N-oxide (6935-29-1) + potassium cyanide (151-50-8) → 2,3-diethynylquinoxaline (91-19-0) + 6-chloroquinoxaline (5448-43-1) + quinoxaline-6-carbonitrile (23088-24-6) + quinoxaline-2-carbonitrile (7483-33-2)

Guidance literature:

With benzoyl chloride; tetrabutyl-ammonium chloride; In chloroform; water; for 16h; Yield given. Further byproducts given. Yields of byproduct given; Ambient temperature;

DOI:10.1016/S0040-4020(01)85794-X

Reference yield:

benzoyl cyanide (613-90-1) + quinoxaline-N-oxide (6935-29-1) → 2,3-diethynylquinoxaline (91-19-0) + quinoxaline-6-carbonitrile (23088-24-6) + quinoxaline-2-carbonitrile (7483-33-2)

Guidance literature:

In xylene; for 2h; Yield given. Yields of byproduct given; Heating;

DOI:10.1016/S0040-4020(01)85794-X

Reference yield:

quinoxaline-N-oxide (6935-29-1) + trimethylsilyl cyanide (7677-24-9) → 2,3-diethynylquinoxaline (91-19-0) + 2-chloroquinoxaline (1448-87-9) + quinoxaline-6-carbonitrile (23088-24-6) + quinoxaline-5-carbonitrile (77130-32-6) + 2-hydroxyquinoxaline (1196-57-2,144499-26-3) + quinoxaline-2-carbonitrile (7483-33-2)

Guidance literature:

With benzoyl chloride; In dichloromethane; for 3h; Product distribution; Ambient temperature; different cyanides, reagents, catalyst, solvents, reaction times and temperatures;

DOI:10.1016/S0040-4020(01)85794-X

upstream raw materials:

benzoyl cyanide

quinoxaline-N-oxide

trimethylsilyl cyanide

potassium cyanide

Downstream raw materials:

C₁₇H₁₃N₅

C₁₇H₁₃N₅

C₁₆H₁₀FN₅

C₁₆H₁₀FN₅

Refernces