5448-43-1 Usage
General Description
6-Chloroquinoxaline is a chemical compound with the molecular formula C8H5ClN2. It is a heterocyclic aromatic compound containing a quinoxaline ring with a chlorine substituent at the 6-position. The compound is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It has also been studied for its potential biological and pharmacological properties. 6-Chloroquinoxaline is known for its diverse reactivity and has been utilized in various organic transformations and reactions. Additionally, it has shown potential as a building block for the development of new synthetic compounds with valuable industrial and medicinal applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5448-43-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5448-43:
(6*5)+(5*4)+(4*4)+(3*8)+(2*4)+(1*3)=101
101 % 10 = 1
So 5448-43-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClN2/c9-6-1-2-7-8(5-6)11-4-3-10-7/h1-5H
5448-43-1Relevant articles and documents
AN UNEXPECTED RING-OPENING IN THE REISSERT REACTION ON 2,3-DIPHENYLQUINOXALINE-N-OXIDE.
Nasielski, J.,Heilporn, S.,Nasielski-Hinkens, R.,Tinant, B.,Declercq, J. P.
, p. 7795 - 7804 (2007/10/02)
When quinoxaline-N-oxide 1 is reacted with KCN and benzoyl chloride in water (the Reissert reaction) or methanol, the products are 2-, 5- and 6- chloroquinoxaline (the latter being the major product: 42+/-6percent) and small amounts of 2-cyanoquinoxaline.Using three equivalents of trimethylsilyl cyanide instead of KCN, and dichloromethane as the solvent, leads to a 72percent yield of 2-cyanoquinoxaline.The reaction of trimethylsilyl cyanide and benzoyl chloride with 2,3-diphenylquinoxaline-N-oxide 2 leads to an unexpected ring-opening product 13; its structure is based on spectroscopic data and on an X-ray crystallographic analysis.
