Phe-Ile

Base Information

Chemical Name:Phe-Ile
CAS No.:22951-94-6
Molecular Formula:C15H22 N2 O3
Molecular Weight:278.351
Hs Code.:2924299090
Nikkaji Number:J1.252.441B
Wikidata:Q27144854
Metabolomics Workbench ID:78925
Mol file:22951-94-6.mol

Synonyms:L-Phenylalanyl-L-isoleucine;L-phenylalanyl-L-leucine;Phe-Leu;phenylalanylleucine

Suppliers and Price of Phe-Ile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
H-PHE-ILE-OH 98.00%
5G
$ 1703.63

AHH
H-Phe-Ile-OH 98%
5g
$ 628.00

Total 14 raw suppliers

Chemical Property of Phe-Ile

Chemical Property:

Vapor Pressure:1.77E-11mmHg at 25°C
Refractive Index:1.544
Boiling Point:516.2°C at 760 mmHg
Flash Point:266°C
PSA：92.42000
Density:1.144g/cm³
LogP:2.26310
Storage Temp.:-15°C
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:278.16304257
Heavy Atom Count:20
Complexity:327

Purity/Quality:

98%min ^*data from raw suppliers

H-PHE-ILE-OH 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C(C(=O)O)NC(=O)C(CC1=CC=CC=C1)N
Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)N

Technology Process of Phe-Ile

There total 8 articles about Phe-Ile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: Boc-Phe-Ile-OtBu

: 22951-94-6
Phenylalanyl-isoleucin

Guidance literature:: With trifluoroacetic acid; for 1h; Ambient temperature;
DOI:10.1021/jm00062a009

Reference yield: 82.0%

: 73-32-5,959215-79-3,18875-42-8
L-isoleucine

: 583-47-1,1892-35-9,14825-82-2,37498-95-6
L-Phenylalanin-N-carbonsaeureanhydrid

: 462-60-2
N-carbamoylglycine

: 22951-94-6
Phenylalanyl-isoleucin

Guidance literature:: With potassium hydroxide; potassium borate buffer; In water; at 3 ℃; pH 10.2;

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 71989-23-6,251316-98-0
Fmoc-Ile-OH

: 22951-94-6
Phenylalanyl-isoleucin

Guidance literature:: Fmoc-Ile-OH; With 1-methyl-1H-imidazole; diisopropyl-carbodiimide; at 20 ℃; for 2h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058