2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester

Base Information

• Chemical Name: 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester
• CAS No.: 202336-84-3
• Molecular Formula: C₂₆H₃₃NO₃
• Molecular Weight: 407.553
• Mol file: 202336-84-3.mol

Synonyms:2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester

Chemical Property of 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester

There total 1 articles about 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethylamine (109-89-7) + 2-(5,5-Diphenyl-pent-4-enyl)-malonic acid monoethyl ester (167562-50-7) → 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester (202336-84-3)

Guidance literature:

With oxalyl dichloride; triethylamine; Yield given. Multistep reaction; 1.) benzene, 5 deg C, 2.) Et₂O, 12 h;

DOI:10.1021/jo9717907

Reference yield: 93.0%

2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester (202336-84-3) → 2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid (202336-87-6)

Guidance literature:

With lithium hydroxide; In ethanol; for 5h; Heating;

DOI:10.1021/jo9717907

Reference yield:

2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid ethyl ester (202336-84-3) → 7,7-Diphenyl-hept-6-enoic acid diethylamide (202336-97-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / LiOH / aq. ethanol / 5 h / Heating

2: 77 percent / 0.5 h / 170 - 175 °C

With lithium hydroxide; In ethanol;

DOI:10.1021/jo9717907

upstream raw materials:

diethylamine

2-(5,5-Diphenyl-pent-4-enyl)-malonic acid monoethyl ester

Downstream raw materials:

2-Diethylcarbamoyl-7,7-diphenyl-hept-6-enoic acid

7,7-Diphenyl-hept-6-enoic acid diethylamide