[2-(Ethylsulfanyl)ethyl]benzene

Base Information

• Chemical Name: [2-(Ethylsulfanyl)ethyl]benzene
• CAS No.: 22914-08-5
• Molecular Formula: C10H14 S
• Molecular Weight: 166.287
• Hs Code.: 2930909090
• Mol file: 22914-08-5.mol

Synonyms:Sulfide,ethyl phenethyl (6CI,7CI,8CI); (2-Ethylthioethyl)benzene; Ethyl phenethylsulfide

Chemical Property of [2-(Ethylsulfanyl)ethyl]benzene

Chemical Property:

• PSA: 25.30000
• LogP: 2.98220

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [2-(Ethylsulfanyl)ethyl]benzene

There total 14 articles about [2-(Ethylsulfanyl)ethyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl phenylthioacetate (14476-63-2) → 2-phenylethanol (60-12-8) + <2-(ethylthio)ethyl>benzene (22914-08-5)

Guidance literature:

With tetrabutylammonium borohydride; In chloroform; for 12h; Yields of byproduct given; Heating;

Reference yield: 82.0%

phenylmagnesium bromide + 2-Chloroethyl ethyl sulfide (693-07-2) → <2-(ethylthio)ethyl>benzene (22914-08-5)

Guidance literature:

In diethyl ether; toluene; at 70 ℃;

DOI:10.1021/jo0489869

Reference yield: 82.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + ethanethiol (75-08-1) → <2-(ethylthio)ethyl>benzene (22914-08-5)

Guidance literature:

With 1-pentyl-3-methylimidazolium bromide; at 20 ℃; for 1h; regioselective reaction;

upstream raw materials:

O,O-diethyl S-(2-phenyl)ethyl phosphorodithioate

2-phenylethyl chloride

sodium thioethylate

ethanethiol

Downstream raw materials:

styrene

phenylacetaldehyde

Diethyl disulfide

2-phenylethanol

Refernces

• 1、 Converse, Antonella,Saaidi, Pierre-Loic,Sharpless, K. Barry,Finn. "Nucleophilic substitution by Grignard reagents on sulfur mustards". . p. 7336 - 7339. Retrieved 2007/10/03.
• 2、 Munavalli, S.,Rossman, D. I.,Rohrbaugh, D. K.,Ferguson, C. P.. "Novel reaction of bis(trifluoromethyl)disulfide with organolithium reagents". . p. 155 - 161. Retrieved 2007/10/02.