1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

Base Information

Chemical Name:1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine
CAS No.:1608473-55-7
Molecular Formula:C₁₅H₁₆FN₃S
Molecular Weight:289.377
Hs Code.:

Synonyms:1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

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Chemical Property of 1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

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Technology Process of 1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

There total 3 articles about 1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 100959-70-4
C₇H₁₃N₃S

: 1608473-55-7
1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

Guidance literature:: With α-halo-4'-fluoroacetophenone, halo= Cl, Br; In methanol; at 90 ℃; for 0.166667h; Microwave irradiation; Sealed tube;
DOI:10.1016/j.bmc.2014.03.042

Reference yield: 81.0%

: 100959-70-4
C₇H₁₃N₃S

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 1608473-55-7
1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

Guidance literature:: C₇H₁₃N₃S; 2-bromo-4'-fluoroacetophenone; In methanol; for 0.0166667h;

In methanol; at 90 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1016/j.ejmech.2014.04.042

Reference yield:

: 1757-42-2,6195-92-2
3-methyl-cyclopentanone

: 1608473-55-7
1-(4-(4-fluorophenyl)thiazol-2-yl)-2-(3-methylcyclopentylidene)hydrazine

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / ethanol / 0.01 h

1.2: 0.08 h / 103 °C / Microwave irradiation

2.1: methanol / 0.02 h

2.2: 0.17 h / 90 °C / Microwave irradiation

With acetic acid; In methanol; ethanol; 2.1: |Hantzsch Thiazole Synthesis / 2.2: |Hantzsch Thiazole Synthesis;
DOI:10.1016/j.ejmech.2014.04.042