4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Base Information

Chemical Name:4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine
CAS No.:1436405-33-2
Molecular Formula:C₁₇H₁₃ClIN₃O₂
Molecular Weight:453.667
Hs Code.:

Synonyms:4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Suppliers and Price of 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

There total 7 articles about 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1436405-32-1
3-chloro-4-(pyridin-2-ylmethoxy)phenol hydrobromide

: 83410-15-5
4-chloro-5-iodo-6-methyl-pyrimidine

: 1436405-33-2
4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Guidance literature:: With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 2h;
DOI:10.1016/j.bmc.2013.03.053

Reference yield:

: 56-04-2
6-methyl-2-thiouracil

: 1436405-33-2
4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1: dihydrogen peroxide / water / 2 h / 70 - 90 °C

2: sodium hydroxide; iodine / water / 3 h / Reflux

3: trichlorophosphate / diethylene glycol dimethyl ether / 2 h / 90 °C

4: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 2 h / 60 °C

With dihydrogen peroxide; iodine; potassium carbonate; potassium iodide; sodium hydroxide; trichlorophosphate; In diethylene glycol dimethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2013.03.053

Reference yield:

: 3524-87-6,156647-96-0
4-hydroxy-6-methylpyrimidine

: 1436405-33-2
4-(3-chloro-4-(pyridin-2-ylmethoxy)phenoxy)-5-iodo-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide; iodine / water / 3 h / Reflux

2: trichlorophosphate / diethylene glycol dimethyl ether / 2 h / 90 °C

3: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 2 h / 60 °C

With iodine; potassium carbonate; potassium iodide; sodium hydroxide; trichlorophosphate; In diethylene glycol dimethyl ether; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2013.03.053