Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER

Base Information

• Chemical Name: Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER
• CAS No.: 2419-54-7
• Molecular Formula: C25H22 N2 O8
• Molecular Weight: 478.458
• Mol file: 2419-54-7.mol

Synonyms:Asparticacid, N-carboxy-, N,4-dibenzyl p-nitrophenyl ester, L- (6CI,7CI,8CI); a-p-Nitrophenyl b-benzylN-[(benzyloxy)carbonyl]-L-aspartate

Chemical Property of Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER

Chemical Property:

• Vapor Pressure: 5.14E-18mmHg at 25°C
• Melting Point: 76 °C
• Refractive Index: 1.603
• Boiling Point: 673.8°C at 760 mmHg
• PKA: 10.08±0.46(Predicted)
• Flash Point: 361.3°C
• PSA: 140.24000
• Density: 1.332g/cm³
• LogP: 4.65630
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Z-Asp(OBzl)-ONp 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER

There total 3 articles about Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Z-Asp(OBzl)-OH (3479-47-8) → N-(benzyloxycarbonyl)-β-benzyl-L-aspartic acid p-nitrophenyl ester (2419-54-7)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1021/ja01079a018

Reference yield:

Z-Asp(OBzl)-OH (3479-47-8) + 4-Nitrophenyl chloroformate (7693-46-1) → N-(benzyloxycarbonyl)-β-benzyl-L-aspartic acid p-nitrophenyl ester (2419-54-7)

Guidance literature:

Multistep reaction; (i) DMF, (ii) /BRN= 2065292/, Et₃N;

Reference yield:

→ N-(benzyloxycarbonyl)-β-benzyl-L-aspartic acid p-nitrophenyl ester (2419-54-7)

Guidance literature:

Z-L-Asp-Bzl, p-Nitrophenol;

DOI:10.1021/ja00814a039

upstream raw materials:

4-nitro-phenol

Z-Asp(OBzl)-OH

4-Nitrophenyl chloroformate

Downstream raw materials:

N-(N-Benzyloxycarbonyl-O⁴-benzyl-α-L-aspartyl)-D-alaninol

4-benzyl ester of N-(benzyloxycarbonyl)-L-aspartyl-L-alanine methyl ester

(S)-2-((S)-3-Benzyloxycarbonyl-2-benzyloxycarbonylamino-propionylamino)-3-methyl-butyric acid methyl ester

Z-(OBzl)Asp-Leu-OCH₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 2419-54-7 Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send