5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Base Information

Chemical Name:5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine
CAS No.:1370546-07-8
Molecular Formula:C₃₇H₃₆F₃N₃O₁₁
Molecular Weight:755.702
Hs Code.:

Synonyms:5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Suppliers and Price of 5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

There total 2 articles about 5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 108-30-5
succinic acid anhydride

: 1370546-05-6
5-(N-trifluoroacetamidomethyl)-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine

: 1370546-07-8
5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Guidance literature:: With pyridine; dmap; at 20 ℃; for 48h;
DOI:10.1016/j.bmcl.2012.03.024

Reference yield:

: 137552-29-5
5-(azidomethyl)-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyuridine

: 1370546-07-8
5-(N-trifluoroacetamidomethyl)-2'-deoxy-3'-O-succinyl-5'-O-(4,4'-dimethoxytrityl)uridine

Guidance literature:: Multi-step reaction with 3 steps

1: 5%-palladium/activated carbon; hydrogen / methanol / 12 h / 20 °C

2: pyridine / 5 h / 20 °C

3: pyridine; dmap / 48 h / 20 °C

With pyridine; dmap; 5%-palladium/activated carbon; hydrogen; In methanol;
DOI:10.1016/j.bmcl.2012.03.024