1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether

Base Information

• Chemical Name: 1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether
• CAS No.: 174318-91-3
• Molecular Formula: C₂₉H₂₇NO₅
• Molecular Weight: 469.537
• Mol file: 174318-91-3.mol

Synonyms:1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether

Chemical Property of 1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether

Chemical Property:

Purity/Quality:

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Technology Process of 1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether

There total 1 articles about 1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

(E)-3,4-dibenzyloxy-β-nitrostyrene (1699-54-3) + sodium phenyl-methanolate (20194-18-7) → 1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether (174318-91-3)

Guidance literature:

In benzyl alcohol; Ambient temperature;

DOI:10.1016/0223-5234(96)88314-0

Reference yield: 54.0%

1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether (174318-91-3) → 2-benzyloxy-2-(3,4-dibenzyloxyphenyl)ethylamine (174318-97-9)

Guidance literature:

With hydrogen; platinum on activated charcoal; In ethanol; for 20h; under 760 Torr;

DOI:10.1016/0223-5234(96)88314-0

Reference yield:

1-(3,4-dibenzyloxyphenyl)-2-nitroethylbenzyl ether (174318-91-3) → 2-benzyloxy-2-(3,4-dihydroxyphenyl)ethylamine

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / H₂ / 10percent Pt/C / ethanol / 20 h / 760 Torr

2: 95 percent / H₂ / 5percent Pd/C / ethanol / 2.5 h / 760 Torr

With hydrogen; palladium on activated charcoal; platinum on activated charcoal; In ethanol;

DOI:10.1016/0223-5234(96)88314-0

upstream raw materials:

(E)-3,4-dibenzyloxy-β-nitrostyrene

sodium phenyl-methanolate

Downstream raw materials:

2-benzyloxy-2-(3,4-dibenzyloxyphenyl)ethylamine

Refernces