syn 3,4-diphenylcyclohex-2-enone oxime tosylate

Base Information

• Chemical Name: syn 3,4-diphenylcyclohex-2-enone oxime tosylate
• CAS No.: 187028-47-3
• Molecular Formula: C₂₅H₂₃NO₃S
• Molecular Weight: 417.529
• Mol file: 187028-47-3.mol

Synonyms:syn 3,4-diphenylcyclohex-2-enone oxime tosylate

Chemical Property of syn 3,4-diphenylcyclohex-2-enone oxime tosylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of syn 3,4-diphenylcyclohex-2-enone oxime tosylate

There total 3 articles about syn 3,4-diphenylcyclohex-2-enone oxime tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

syn-3,4-diphenylyclohexenone oxime (94004-18-9) + p-toluenesulfonyl chloride (98-59-9) → syn 3,4-diphenylcyclohex-2-enone oxime tosylate (187028-47-3)

Guidance literature:

With pyridine; In dichloromethane; for 18h;

DOI:10.1002/jhet.5570330615

Reference yield:

phenyl benzyl ketone (451-40-1) → syn 3,4-diphenylcyclohex-2-enone oxime tosylate (187028-47-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / KOH / tetrahydrofuran; aq. ethanol / 1.) from -30 deg C to RT, 2.) 50 deg C 1 h

2: 15 percent / NH₂OH*HCl, pyridine / ethanol; H₂O / 0.5 h / Heating

3: 98 percent / pyridine / CH₂Cl₂ / 18 h

With pyridine; potassium hydroxide; hydroxylamine hydrochloride; In tetrahydrofuran; ethanol; dichloromethane; water;

DOI:10.1002/jhet.5570330615

Reference yield:

3,4-diphenyl-2-cyclohexen-1-one (10468-67-4) → syn 3,4-diphenylcyclohex-2-enone oxime tosylate (187028-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 15 percent / NH₂OH*HCl, pyridine / ethanol; H₂O / 0.5 h / Heating

2: 98 percent / pyridine / CH₂Cl₂ / 18 h

With pyridine; hydroxylamine hydrochloride; In ethanol; dichloromethane; water;

DOI:10.1002/jhet.5570330615

upstream raw materials:

syn-3,4-diphenylyclohexenone oxime

p-toluenesulfonyl chloride

phenyl benzyl ketone

3,4-diphenyl-2-cyclohexen-1-one

Downstream raw materials:

4,5-diphenyl 1,5,6,7-tetrahydroazepin-2-one

Refernces