3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

Base Information

• Chemical Name: 3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid
• CAS No.: 188814-26-8
• Molecular Formula: C₂₄H₁₉Cl₂NO₄
• Molecular Weight: 456.325
• European Community (EC) Number: 969-315-7
• Mol file: 188814-26-8.mol

Synonyms:188814-26-8;3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid;SCHEMBL2038176;BEKZHTVXEZMGPB-UHFFFAOYSA-N;EN300-650855;3-(3,5-dichlorophenyl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid;3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid

Chemical Property of 3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

Chemical Property:

• XLogP3: 5.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 455.0691135
• Heavy Atom Count: 31
• Complexity: 615

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C4=CC(=CC(=C4)Cl)Cl

Technology Process of 3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

There total 1 articles about 3-(3,5-dichlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(fluorenylmethoxy)carbonyl chloride (28920-43-6) + (+/-)-3-amino-3-(3,5-dichlorophenyl)propanoic acid (188812-95-5,1080673-41-1) → 3-[N-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-3-(3,5-dichloro)-phenylpropionic acid (188814-26-8)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; at 20 ℃; for 24h;

DOI:10.1021/jm0004953

upstream raw materials:

(fluorenylmethoxy)carbonyl chloride

(+/-)-3-amino-3-(3,5-dichlorophenyl)propanoic acid