Technology Process of 1,3-dihydroxy-2-[11-(4-iodophenoxy)undecyl]propane
There total 5 articles about 1,3-dihydroxy-2-[11-(4-iodophenoxy)undecyl]propane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
tetrahydrofuran; hexane;
at -15 ℃;
for 26h;
Schlenk technique;
DOI:10.1246/cl.2011.1450
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 44 h / 50 °C / Schlenk technique
2.1: triethylamine; dmap / dichloromethane / 45 h / 0 - 20 °C / Schlenk technique
3.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide / 0.25 h / 0 - 20 °C / Schlenk technique; Inert atmosphere
3.2: 9 h / Schlenk technique; Inert atmosphere; Reflux
4.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 26 h / -15 °C / Schlenk technique
With
dmap; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1246/cl.2011.1450
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 44 h / 50 °C / Schlenk technique
2.1: triethylamine; dmap / dichloromethane / 45 h / 0 - 20 °C / Schlenk technique
3.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide / 0.25 h / 0 - 20 °C / Schlenk technique; Inert atmosphere
3.2: 9 h / Schlenk technique; Inert atmosphere; Reflux
4.1: diisobutylaluminium hydride / tetrahydrofuran; hexane / 26 h / -15 °C / Schlenk technique
With
dmap; sodium hydride; diisobutylaluminium hydride; potassium carbonate; triethylamine;
In
tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1246/cl.2011.1450
![diethyl 2-[11-(4-iodophenoxy)undecyl]malonate](/Databaselist/images/loading.webp)
