2-Amino-4-phenoxy-6-methylpyrimidine

Base Information

Chemical Name:2-Amino-4-phenoxy-6-methylpyrimidine
CAS No.:22370-25-8
Molecular Formula:C11H11N3O
Molecular Weight:201.228
Hs Code.:2933599090
DSSTox Substance ID:DTXSID60350356
Wikidata:Q82126245
ChEMBL ID:CHEMBL1330891
Mol file:22370-25-8.mol

Synonyms:2-Amino-4-phenoxy-6-methylpyrimidine;22370-25-8;4-methyl-6-phenoxypyrimidin-2-amine;MLS000060860;ChemDiv2_003414;Cambridge id 5484994;Oprea1_388163;SCHEMBL4528068;CHEMBL1330891;DTXSID60350356;HMS1378L04;HMS2430H12;4-methyl-6-phenoxy-2-pyrimidinamine;4-methyl-6-phenoxy-pyrimidin-2-amine;AKOS001586902;SDCCGMLS-0031116.P002;SMR000069726;FT-0638217;AB00086778-01;A816164;AG-670/25003526;SR-01000396926;SR-01000396926-1

Suppliers and Price of 2-Amino-4-phenoxy-6-methylpyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINO-4-PHENOXY-6-METHYLPYRIMIDINE 98.00%
10G
$ 1732.50

American Custom Chemicals Corporation
2-AMINO-4-PHENOXY-6-METHYLPYRIMIDINE 98.00%
5G
$ 1183.88

AHH
2-Amino-4-phenoxy-6-methylpyrimidine 98%
5g
$ 180.00

Total 12 raw suppliers

Chemical Property of 2-Amino-4-phenoxy-6-methylpyrimidine

Chemical Property:

Vapor Pressure:1.98E-06mmHg at 25°C
Melting Point:194-195 °C
Refractive Index:1.619
Boiling Point:394.4 °C at 760 mmHg
PKA:5.63±0.10(Predicted)
Flash Point:192.3 °C
PSA：61.03000
Density:1.219 g/cm³
LogP:2.74070
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:201.090211983
Heavy Atom Count:15
Complexity:194

Purity/Quality:

97% ^*data from raw suppliers

2-AMINO-4-PHENOXY-6-METHYLPYRIMIDINE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)N)OC2=CC=CC=C2

Technology Process of 2-Amino-4-phenoxy-6-methylpyrimidine

There total 4 articles about 2-Amino-4-phenoxy-6-methylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 5600-21-5
2-amino-6-methyl-4-chloropyrimidine

: 108-95-2,27073-41-2
phenol

: 22370-25-8
4-methyl-6-phenoxypyrimidin-2-amine

Guidance literature:: With potassium hydroxide; In water; at 165 ℃; for 0.0833333h; Microwave;

Reference yield: 67.0%

: 2-amino-6-methylpyrimidin-4-yl 4-methylbenzenesulfonate

: 108-95-2,27073-41-2
phenol

: 22370-25-8
4-methyl-6-phenoxypyrimidin-2-amine

Guidance literature:: at 140 ℃; for 1h;
DOI:10.1134/S1070428015100127

Reference yield:

: 3977-29-5
2-amino-6-methyl-3H-pyrimidin-4-one

: 22370-25-8
4-methyl-6-phenoxypyrimidin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water / 3 h / 15 - 20 °C

2: 1 h / 140 °C

With sodium hydroxide; In water;
DOI:10.1134/S1070428015100127