1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine

Base Information

Chemical Name:1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine
CAS No.:27098-24-4
Molecular Formula:C44H84 N O8 P
Molecular Weight:786.127
Hs Code.:
DSSTox Substance ID:DTXSID001230503
Wikidata:Q27105102
Metabolomics Workbench ID:13478
Mol file:27098-24-4.mol

Synonyms:1-stearoyl-(2-linoleoyl)-sn-glycero-3-phosphocholine;1-stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine;1-stearoyl-2-linoleoylphosphatidylcholine;SLPC;SLPTC

Suppliers and Price of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00%
5MG
$ 502.87

Total 5 raw suppliers

Chemical Property of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：121.00000
Density:g/cm³
LogP:12.79440
Storage Temp.:-20°C
XLogP3:14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:42
Exact Mass:785.59345564
Heavy Atom Count:54
Complexity:972

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Lipids -> Ambiguous Lipids
Canonical SMILES:CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
Isomeric SMILES:CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC
Uses 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine s used in the preparation of a fiber with resistance to respiratory viral disease. The fiber has exogenous pulmonary surfactant which can enter the body through breathing and play an antiviral role. 18:0-18:2 PC is suitable for use:in the preparation of large unilamellar vesiclesin the preparation of liposomesto prepare oxidised phospholipid by 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) for multiple reaction monitoring (MRM) analysis

Technology Process of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine

There total 6 articles about 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphatidylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-0-triphenylmethyl-sn-glycero-3-phosphocholine: 1-0-triphenylmethyl-sn-glycero-3-phosphocholine

: 2-linoleoyl-sn-glycero-3-phosphocholine

: 638-08-4
stearic anhydride

: 27098-24-4,70106-57-9,923-59-1
trimethyl (2-{[(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propylphosphonato]oxy}ethyl)azanium

Guidance literature:

Reference yield: 77.0%

: 60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3
linoleic acid

: 19420-57-6,5655-17-4
1-stearoyl-sn-glycero-3-phosphocholine

: 27098-24-4,70106-57-9,923-59-1
trimethyl (2-{[(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propylphosphonato]oxy}ethyl)azanium

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In chloroform; at 20 ℃; for 120h;
DOI:10.1111/febs.14807

Reference yield:

: 111-63-7,9003-95-6
vinyl stearate

: 27098-24-4,70106-57-9,923-59-1
trimethyl (2-{[(2R)-2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]-3-(octadecanoyloxy)propylphosphonato]oxy}ethyl)azanium

Guidance literature:: Multi-step reaction with 3 steps

1: lipase / propan-2-ol

2: 1.) POCl₃, 3.) H₂O, 4.) H₂ / 4.) Pd(OH)2/C / 1.) Et₃N, 2.) pyridine, 4.) H₂O, Ch₃OH

3: DCC, DMAP / CHCl₃

With dmap; water; hydrogen; dicyclohexyl-carbodiimide; lipase; trichlorophosphate; palladium dihydroxide; In chloroform; isopropyl alcohol;
DOI:10.1271/bbb.60.1916