Technology Process of methyl 3-{3,4-bis[3-(4-dodecyl-1-oxyphenyl)propyl-1-oxy]phenyl}propionate
There total 11 articles about methyl 3-{3,4-bis[3-(4-dodecyl-1-oxyphenyl)propyl-1-oxy]phenyl}propionate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 16h;
DOI:10.1021/ja060062a
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / K2CO3 / dimethylformamide / 12 h / 80 °C
2: 96 percent / LiAlH4 / tetrahydrofuran / 0.5 h / 0 °C
3: 91 percent / CBr4; PPh3 / CH2Cl2 / 2 h / 0 °C
4: 86 percent / K2CO3 / dimethylformamide / 16 h / 80 °C
With
lithium aluminium tetrahydride; carbon tetrabromide; potassium carbonate; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja060062a
- Guidance literature:
-
Multi-step reaction with 8 steps
1: H2SO4 / Heating
2: 86 percent / K2CO3 / dimethylformamide / 8 h / 75 °C
3: 94 percent / LiAlH4 / tetrahydrofuran / 0 - 20 °C
4: pyridinium chlorochromate / CH2Cl2 / 20 °C
5: 90 percent / morpholine; AcOH / Heating
6: 95 percent / p-toluenesulfonic acid monohydrate / 24 h / Heating
7: 91 percent / H2 / Pd/C / ethanol
8: 86 percent / K2CO3 / dimethylformamide / 16 h / 80 °C
With
morpholine; lithium aluminium tetrahydride; sulfuric acid; hydrogen; potassium carbonate; toluene-4-sulfonic acid; acetic acid; pyridinium chlorochromate;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;
1: Fisher esterification / 5: Knoevenagel condensation;
DOI:10.1021/ja060062a