C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾

Base Information

• Chemical Name: C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾
• CAS No.: 1621086-60-9
• Molecular Formula: C₁₇H₁₃N₄O₃*Na
• Molecular Weight: 344.305
• Mol file: 1621086-60-9.mol

Synonyms:C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾

Chemical Property of C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾

There total 3 articles about C₁₇H₁₃N₄O₃^(1-)*Na⁽¹⁺⁾ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.2%

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) + edaravone (89-25-8) → C17H13N4O3(1-)*Na(1+) (1621086-60-9)

Guidance literature:

4-amino-benzoic acid; With sodium hydroxide; sodium nitrite; In water; at 20 ℃;

With hydrogenchloride; In water; at 0 - 5 ℃;

edaravone; With sodium carbonate; at 0 - 5 ℃; for 3h; pH=8.5 - 9;

DOI:10.1016/j.cclet.2014.03.045

Reference yield:

C19H18N4O3 (332402-46-7) → C17H13N4O3(1-)*Na(1+) (1621086-60-9)

Guidance literature:

With sodium hydroxide; In water;

DOI:10.1016/j.cclet.2014.03.045

Reference yield:

C17H13ClN4O2 (127811-58-9) → C17H13N4O3(1-)*Na(1+) (1621086-60-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / 1.5 h / Molecular sieve; Reflux

2: sodium hydroxide / water

With potassium carbonate; sodium hydroxide; In water;

DOI:10.1016/j.cclet.2014.03.045

upstream raw materials:

C₁₉H₁₈N₄O₃

4-amino-benzoic acid

edaravone

C₁₇H₁₃ClN₄O₂

Downstream raw materials:

1-phenyl-3-methyl-4-((4-carboxyphenyl)hydrazono)pyrazol-5-one

C₁₇H₁₃ClN₄O₂