2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

Base Information

Chemical Name:2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester
CAS No.:245364-65-2
Molecular Formula:C₁₅H₂₂FNO₄S
Molecular Weight:331.408
Hs Code.:

2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid <i>tert</i>-butyl ester

Synonyms:2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

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Chemical Property of 2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

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Technology Process of 2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

There total 1 articles about 2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 349-88-2
4-Fluorobenzenesulfonyl chloride

: 13518-40-6
L-valine tert-butylester hydrochloride

: 245364-65-2
2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

Guidance literature:: With pyridine;
DOI:10.1016/S0960-894X(99)00311-X

Reference yield: 100.0%

: 100-39-0
benzyl bromide

: 245364-65-2
2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

: 245364-79-8
2-[benzyl-(4-fluoro-benzenesulfonyl)-amino]-3-methyl-butyric acid tert-butyl ester

Guidance literature:: With polystyrene-bound 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; In dichloromethane;
DOI:10.1016/S0960-894X(99)00311-X

Reference yield: 100.0%

: 104-81-4
4-Methylbenzyl bromide

: 245364-65-2
2-(4-fluoro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester

: 245364-85-6
2-[(4-fluoro-benzenesulfonyl)-(4-methyl-benzyl)-amino]-3-methyl-butyric acid tert-butyl ester

Guidance literature:: With polystyrene-bound 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; In dichloromethane;
DOI:10.1016/S0960-894X(99)00311-X