2,2-diphenyl-5-hexenenitrile

Base Information

• Chemical Name: 2,2-diphenyl-5-hexenenitrile
• CAS No.: 171819-23-1
• Molecular Formula: C₁₈H₁₇N
• Molecular Weight: 247.34
• Mol file: 171819-23-1.mol

Synonyms:2,2-diphenyl-5-hexenenitrile

Chemical Property of 2,2-diphenyl-5-hexenenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-diphenyl-5-hexenenitrile

There total 4 articles about 2,2-diphenyl-5-hexenenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-4-butene (5162-44-7) + Diphenylacetonitrile (86-29-3) → 2,2-diphenyl-5-hexenenitrile (171819-23-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; Inert atmosphere;

DOI:10.1021/ja9031659

Reference yield:

Bromodiphenylmethane (776-74-9) → 2,2-diphenyl-5-hexenenitrile (171819-23-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 2 h / 0 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 60 °C / Inert atmosphere

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1039/d1cc06687k

Reference yield:

Diphenylacetonitrile (86-29-3) → 2,2-diphenyl-5-hexenenitrile (171819-23-1)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; Heating;

DOI:10.1021/jo00123a013

upstream raw materials:

Diphenylacetonitrile

1-bromo-4-butene

chlorobenzene

Bromodiphenylmethane

Downstream raw materials:

2,2-diphenyl-5-hexenal

C₁₉H₂₁NO

2,2-diphenyl-hex-5-enylamine hydrochloride salt

1-amino-2,2-diphenyl-4-hexene