4-Chloro-7-iodoquinoline

Base Information

Chemical Name:4-Chloro-7-iodoquinoline
CAS No.:22200-50-6
Molecular Formula:C9H5ClIN
Molecular Weight:289.503
Hs Code.:2933499090
DSSTox Substance ID:DTXSID40442228
Wikidata:Q82259394
Mol file:22200-50-6.mol

Synonyms:4-chloro-7-iodoquinoline;22200-50-6;7-IODO-4-CHLOROQUINOLINE;SCHEMBL1618081;DTXSID40442228;JKZGHMPCBJVWEL-UHFFFAOYSA-N;MFCD00511002;AKOS015851098;DS-1501;SB71490;AM803535;CS-0037243;FT-0649597;EN300-7409242;A878653

Suppliers and Price of 4-Chloro-7-iodoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
7-Iodo-4-chloroquinoline >95%
1g
$ 450.00

Matrix Scientific
7-Iodo-4-chloroquinoline >95%
5g
$ 1350.00

Crysdot
7-Iodo-4-chloroquinoline 97%
10g
$ 682.00

Crysdot
7-Iodo-4-chloroquinoline 97%
5g
$ 379.00

Chemenu
7-Iodo-4-chloroquinoline 97%
10g
$ 644.00

Chemenu
7-Iodo-4-chloroquinoline 97%
5g
$ 358.00

Ambeed
7-Iodo-4-chloroquinoline 97%
1g
$ 127.00

Ambeed
7-Iodo-4-chloroquinoline 97%
250mg
$ 51.00

Ambeed
7-Iodo-4-chloroquinoline 97%
5g
$ 399.00

Ambeed
7-Iodo-4-chloroquinoline 97%
10g
$ 723.00

Total 37 raw suppliers

Chemical Property of 4-Chloro-7-iodoquinoline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:101-102 °C
Refractive Index:1.727
Boiling Point:338.368 °C at 760 mmHg
PKA:2.05±0.27(Predicted)
Flash Point:158.439 °C
PSA：12.89000
Density:1.92 g/cm³
LogP:3.49280
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:288.91552
Heavy Atom Count:12
Complexity:165

Purity/Quality:

97% ^*data from raw suppliers

7-Iodo-4-chloroquinoline >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CN=C2C=C1I)Cl

Technology Process of 4-Chloro-7-iodoquinoline

There total 8 articles about 4-Chloro-7-iodoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 22297-71-8
7-iodo-quinolin-4-ol

: 22200-50-6
4-chloro-7-iodoquinoline

Guidance literature:: With thionyl chloride; N,N-dimethyl-formamide; at 90 ℃; for 18h;

Reference yield:

: 22200-48-2
4-hydroxy-7-iodo-quinoline-3-carboxylic acid ethyl ester

: 22200-50-6
4-chloro-7-iodoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 2 N NaOH / Heating

2: diphenyl ether / 1 h / Heating

3: POCl₃ / 1.17 h / 100 - 110 °C

With sodium hydroxide; trichlorophosphate; In diphenylether;
DOI:10.1021/jm980146x

Reference yield:

: 626-01-7
3-Iodoaniline

: 22200-50-6
4-chloro-7-iodoquinoline

Guidance literature:: Multi-step reaction with 5 steps

3: aqueous NaOH

4: 330 °C

5: phosphoryl chloride

With sodium hydroxide; trichlorophosphate;
DOI:10.1021/ja01177a504