(R)-1-phenoxy>-2-acetoxy-3-chloropropanol

Base Information

Chemical Name:(R)-1-phenoxy>-2-acetoxy-3-chloropropanol
CAS No.:144017-03-8
Molecular Formula:C₁₇H₂₃ClO₅
Molecular Weight:342.82
Hs Code.:

(R)-1-<p-<(butoxycarbonyl)methyl>phenoxy>-2-acetoxy-3-chloropropanol

Synonyms:(R)-1-phenoxy>-2-acetoxy-3-chloropropanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-phenoxy>-2-acetoxy-3-chloropropanol

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Technology Process of (R)-1-phenoxy>-2-acetoxy-3-chloropropanol

There total 3 articles about (R)-1-phenoxy>-2-acetoxy-3-chloropropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 156-38-7
4-hydroxyphenylacetate

: 144017-03-8
(R)-1-phenoxy>-2-acetoxy-3-chloropropanol

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaHSO₃ / Heating

2: 1) pyridine, 2) HCl(g) / 1) RT, 48 h, 2a) CHCl₃, 0 to 5 deg C, 1 h, 2b) RT, 2 h

With pyridine; hydrogenchloride; sodium hydrogensulfite;
DOI:10.1021/jo00048a040

Reference yield:

: 79419-46-8
4-hydroxyphenylacetic acid butyl este

: 106-89-8,24969-06-0,13403-37-7
epichlorohydrin

: 144015-98-5
(S)-1-phenoxy>-3-chloropropan-2-ol

: 144017-03-8
(R)-1-phenoxy>-2-acetoxy-3-chloropropanol

Guidance literature:: With pyridine; hydrogenchloride; Yield given. Multistep reaction. Yields of byproduct given; 1) RT, 48 h, 2a) CHCl₃, 0 to 5 deg C, 1 h, 2b) RT, 2 h;
DOI:10.1021/jo00048a040