N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide

Base Information

• Chemical Name: N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide
• CAS No.: 83728-57-8
• Molecular Formula: C₂₄H₂₃N₃O₃
• Molecular Weight: 401.465
• Mol file: 83728-57-8.mol

Synonyms:N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide

Chemical Property of N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide

There total 2 articles about N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

N-(4-methylphenyl)benzimidoyl chloride (15999-95-8) + 4-morpholin-4-yl-pyridine-2-carboxylic acid (66933-68-4) → N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide (83728-57-8)

Guidance literature:

With triethylamine;

Reference yield:

N-Cyclopentyl-N-(4-morpholin-4-yl-pyridine-2-carbonyl)-benzamide (82776-75-8) → N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide (83728-57-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 240 h / Ambient temperature

2: 63 percent / triethylamine

With triethylamine;

Reference yield:

N-(4-Morpholin-4-yl-pyridine-2-carbonyl)-N-p-tolyl-benzamide (83728-57-8) → N-(4-methylphenyl)benzamide (582-78-5) + 4-Morpholin-4-yl-pyridine-2-carboxylic acid cyclopentylamide (82776-69-0)

Guidance literature:

With Cyclopentamine; In dichloromethane; acetonitrile; for 1h; Ambient temperature;

upstream raw materials:

N-(4-methylphenyl)benzimidoyl chloride

4-morpholin-4-yl-pyridine-2-carboxylic acid

N-Cyclopentyl-N-(4-morpholin-4-yl-pyridine-2-carbonyl)-benzamide

Downstream raw materials:

N-(4-methylphenyl)benzamide

(4-Morpholin-4-yl-pyridin-2-yl)-pyrrolidin-1-yl-methanone

methyl 2-(morpholin-4-yl)pyridine-4-carboxylate

4-Morpholin-4-yl-pyridine-2-carboxylic acid cyclopentylamide