3,5-Dimethoxystilbene

Base Information

• Chemical Name: 3,5-Dimethoxystilbene
• CAS No.: 21956-56-9
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• NSC Number: 43313
• UNII: DWA4D52V24
• DSSTox Substance ID: DTXSID301016205
• Nikkaji Number: J456.344A,J464.986I
• Metabolomics Workbench ID: 125242
• ChEMBL ID: CHEMBL188181
• Mol file: 21956-56-9.mol

Synonyms:3,5-dimethoxystilbene

Chemical Property of 3,5-Dimethoxystilbene

Chemical Property:

• Vapor Pressure: 1.56E-05mmHg at 25°C
• Melting Point: 56.4°C
• Refractive Index: 1.615
• Boiling Point: 376.5°Cat760mmHg
• Flash Point: 150.7°C
• Density: 1.089g/cm³
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 240.115029749
• Heavy Atom Count: 18
• Complexity: 244

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dimethoxystilbene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1)C=CC2=CC=CC=C2)OC
• Isomeric SMILES: COC1=CC(=CC(=C1)/C=C/C2=CC=CC=C2)OC

Technology Process of 3,5-Dimethoxystilbene

There total 78 articles about 3,5-Dimethoxystilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(1-(2-(3,5-dimethoxyphenyl)ethynyl))benzene → (E)-3,5-dimethoxystilbene (21956-56-9)

Guidance literature:

With palladium diacetate; (R_P,R_P)-1,2-bis[(o-anisyl)(phenyl)phosphino]ethane; In ethanol; acetonitrile; at 145 ℃; for 36h;

Reference yield: 93.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1-bromo-3,5-dimethoxybenzene (20469-65-2) → (E)-3,5-dimethoxystilbene (21956-56-9)

Guidance literature:

With potassium carbonate; In water; dimethyl sulfoxide; at 90 ℃; for 10h; Green chemistry;

DOI:10.1039/c4gc00412d

Reference yield: 92.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + benzyl bromide (100-39-0) → 1-phenyl-2-(3,5-dimethoxyphenyl)ethene (78916-49-1,21956-55-8,21956-56-9)

Guidance literature:

With tris(bipyridine)ruthenium(II) dichloride hexahydrate; potassium carbonate; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Schlenk technique; Inert atmosphere; Irradiation;

upstream raw materials:

1,3-dimethoxy-5-[(1Z)-2-phenylethenyl]benzene

pinosylvin

dimethyl sulfate

3-methoxy-5-[(E)-2-phenylvinyl]phenol

Downstream raw materials:

4-bromo-3.5-dimethoxy-trans-stilbene

1,3-dimethoxy-5-(2-phenylethyl)benzene

pinosylvin

3-methoxy-5-[(E)-2-phenylvinyl]phenol