TRANS-4-TERT-BUTYLCYCLOHEXANOL

Base Information

• Chemical Name: TRANS-4-TERT-BUTYLCYCLOHEXANOL
• CAS No.: 21862-63-5
• Molecular Formula: C10H20 O
• Molecular Weight: 156.268
• Hs Code.: 2906190090
• Mol file: 21862-63-5.mol

Synonyms:Cyclohexanol,4-tert-butyl-, trans- (8CI); trans-1-tert-Butylcyclohexan-4-ol;trans-4-tert-Butyl-1-cyclohexanol; trans-4-tert-Butylcyclohexanol;trans-4-tert-Butylcyclohexyl alcohol; trans-p-tert-Butylcyclohexanol

Chemical Property of TRANS-4-TERT-BUTYLCYCLOHEXANOL

Chemical Property:

• Vapor Pressure: 0.74-29Pa at 20-50℃
• Melting Point: 80 °C
• Refractive Index: 1.447
• Boiling Point: 214.2°Cat760mmHg
• PKA: 15.32±0.40(Predicted)
• Flash Point: 105°C
• Density: 0.92g/cm³
• Water Solubility.: <1 g/L (20℃)

Purity/Quality:

99.9% ^*data from raw suppliers

trans-4-tert-Butylcyclohexanol >95.0%(GC) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRANS-4-TERT-BUTYLCYCLOHEXANOL

There total 74 articles about TRANS-4-TERT-BUTYLCYCLOHEXANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-phenyl-propan-1-one (93-55-0) → trans-4-tert-butylcyclohexanol (21862-63-5) + 1-Phenyl-1-propanol (93-54-9)

Guidance literature:

With 2-amino-4-methylpyridine borane; In acetic acid; for 24h; Ambient temperature;

Reference yield: 66.4%

para-tert-butylphenol (98-54-4) → tert-butylcyclohexane (3178-22-1) + trans-4-tert-butylcyclohexanol (21862-63-5) + cis-4-tert-butyl-1-cyclohexanol (937-05-3) + 4-tercbutyl-cyclohexanone (98-53-3)

Guidance literature:

With hydrogen; Rh on carbon; In isopropyl alcohol; at 39.84 ℃; for 1h; under 15001.5 Torr; Further Variations:; Solvents; Pressures; Reagents; Product distribution;

DOI:10.1016/j.jcat.2007.08.011

Reference yield: 63.0%

4'-(1,1-dimethylethyl)spiro[4H-3,1-benzoxaselenin-2,1'-cyclohexan]-4-one (634905-71-8) → trans-4-tert-butylcyclohexanol (21862-63-5) + cis-4-tert-butyl-1-cyclohexanol (937-05-3)

Guidance literature:

With triethyl borane; tri-n-butyl-tin hydride; In benzene; at 20 ℃; for 84h;

DOI:10.1081/SCC-120020210

upstream raw materials:

4-tercbutyl-cyclohexanone

2,2,2-trifluoroethanol

toluene-4-sulfonic acid-(trans-4-tert-butyl-cyclohexyl ester)

cis-4-tert-butylcyclohexyl tosylate

Downstream raw materials:

trans-1-tert-butyl-4-butyryloxy-cyclohexane

phthalic acid mono-(trans-4-tert-butyl-cyclohexyl ester)

cis-1-bromo-4-tert-butylcyclohexane

trans,cis-1,2-dibromo-4-tert-butylcyclohexane