Technology Process of methyl 23-benzyloxy-3,3-ethylenedioxyurs-12-en-28-oate
There total 8 articles about methyl 23-benzyloxy-3,3-ethylenedioxyurs-12-en-28-oate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; potassium hydride;
In
tetrahydrofuran;
for 28h;
Heating;
DOI:10.1021/jo0008688
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: diethyl ether; tetrahydrofuran
2.1: Jones / acetone
3.1: NH2OH*HCl; NaOAc / methanol; CH2Cl2
4.1: Na2PdCl4; NaOAc / acetic acid / 72 h
4.2: DMAP; Et3N / CH2Cl2 / 0.75 h / 20 °C
4.3: 1.92 g / Pb(OAc)4 / pyridine; tetrahydrofuran; acetic acid / 16 h / 20 °C
5.1: 98 percent / Na2CO3 / methanol / 16 h / 20 °C
6.1: 88 percent / 20percent HCl; NH4OAc / TiCl3 / H2O; tetrahydrofuran / 4 h / 20 °C
7.1: 99 percent / PPTS; MS / benzene / 20 h / Heating
8.1: 94 percent / KH; n-Bu4NI / tetrahydrofuran / 28 h / Heating
With
sodium tetrachloropalladate(II); hydroxylamine hydrochloride; ammonium acetate; sodium acetate; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium carbonate;
titanium(III) chloride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; acetic acid; acetone; benzene;
1.1: Methylation / 2.1: Oxidation / 3.1: oximation / 4.1: complexation / 4.2: Acetylation / 4.3: Oxidation / 5.1: Deacetylation / 6.1: Oxidation / 7.1: Condensation / 8.1: Alkylation;
DOI:10.1021/jo0008688
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: Jones / acetone
2.1: NH2OH*HCl; NaOAc / methanol; CH2Cl2
3.1: Na2PdCl4; NaOAc / acetic acid / 72 h
3.2: DMAP; Et3N / CH2Cl2 / 0.75 h / 20 °C
3.3: 1.92 g / Pb(OAc)4 / pyridine; tetrahydrofuran; acetic acid / 16 h / 20 °C
4.1: 98 percent / Na2CO3 / methanol / 16 h / 20 °C
5.1: 88 percent / 20percent HCl; NH4OAc / TiCl3 / H2O; tetrahydrofuran / 4 h / 20 °C
6.1: 99 percent / PPTS; MS / benzene / 20 h / Heating
7.1: 94 percent / KH; n-Bu4NI / tetrahydrofuran / 28 h / Heating
With
sodium tetrachloropalladate(II); hydroxylamine hydrochloride; ammonium acetate; sodium acetate; pyridinium p-toluenesulfonate; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium carbonate;
titanium(III) chloride;
In
tetrahydrofuran; methanol; dichloromethane; water; acetic acid; acetone; benzene;
1.1: Oxidation / 2.1: oximation / 3.1: complexation / 3.2: Acetylation / 3.3: Oxidation / 4.1: Deacetylation / 5.1: Oxidation / 6.1: Condensation / 7.1: Alkylation;
DOI:10.1021/jo0008688
