Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine

Base Information

• Chemical Name: Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine
• CAS No.: 95502-66-2
• Molecular Formula: C₁₈H₁₃N₃OS
• Molecular Weight: 319.387
• Mol file: 95502-66-2.mol

Synonyms:Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine

Chemical Property of Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine

There total 3 articles about Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Dihydro-4,5 benzoyl-4 cyano-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine (95502-64-0) + methyl iodide (74-88-4) → Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine (95502-66-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; Petroleum ether; at 0 - 5 ℃; for 2.5h;

DOI:10.1002/jhet.5570210545

Reference yield:

Pyrrolo<1,2-a>thieno<3,2-e>pyrazine (75214-39-0) → Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine (95502-66-2)

Guidance literature:

Multi-step reaction with 2 steps

2: 92 percent / NaH / dimethylformamide; petroleum ether / 2.5 h / 0 - 5 °C

With sodium hydride; In N,N-dimethyl-formamide; Petroleum ether;

DOI:10.1002/jhet.5570210545

Reference yield:

benzoyl chloride (98-88-4) → Benzoyl-4 cyano-5 methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine (95502-66-2)

Guidance literature:

Multi-step reaction with 2 steps

2: 92 percent / NaH / dimethylformamide; petroleum ether / 2.5 h / 0 - 5 °C

With sodium hydride; In N,N-dimethyl-formamide; Petroleum ether;

DOI:10.1002/jhet.5570210545

upstream raw materials:

Dihydro-4,5 benzoyl-4 cyano-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine

methyl iodide

Pyrrolo<1,2-a>thieno<3,2-e>pyrazine

benzoyl chloride

Downstream raw materials:

Methyl-5 pyrrolo<1,2-a>thieno<3,2-e>pyrazine