Technology Process of C48H68O9
There total 15 articles about C48H68O9 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C43H60O8;
With
di(n-butyl)tin oxide;
In
toluene;
for 0.75h;
Heating;
pivaloyl chloride;
In
dichloromethane;
at 0 ℃;
for 1h;
Further stages.;
DOI:10.1016/j.tetlet.2007.07.182
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 92 percent / LiOH*H2O; aq. H2O2 / tetrahydrofuran / 2 h / 20 °C
2.1: 96 percent / H2; K2CO3 / Pd/C / methanol / 0.83 h
3.1: EDC; DMAP / dimethylformamide / 12 h / 50 °C
4.1: ((S)-1-Ph-2-piperidin-1-yl-Et)-(2,2,2-triF-Et)amine; n-BuLi / tetrahydrofuran; hexane / 1 h
4.2: Me3SiCl / 0.58 h / -78 - 0 °C
5.1: 0.310 g / LiAlH4 / tetrahydrofuran / 5 h / Heating
6.1: n-Bu2SnO / toluene / 0.75 h / Heating
6.2: 71 percent / CH2Cl2 / 1 h / 0 °C
With
dmap; lithium hydroxide; lithium aluminium tetrahydride; n-butyllithium; hydrogen; dihydrogen peroxide; di(n-butyl)tin oxide; potassium carbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; hexane; N,N-dimethyl-formamide; toluene;
4.1: Ireland-Claisen rearrngement;
DOI:10.1016/j.tetlet.2007.07.182
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: NaHDMS / tetrahydrofuran / 2 h / -78 °C
1.2: 80 percent / tetrahydrofuran / -78 - -20 °C
2.1: 92 percent / LiOH*H2O; aq. H2O2 / tetrahydrofuran / 2 h / 20 °C
3.1: 96 percent / H2; K2CO3 / Pd/C / methanol / 0.83 h
4.1: EDC; DMAP / dimethylformamide / 12 h / 50 °C
5.1: ((S)-1-Ph-2-piperidin-1-yl-Et)-(2,2,2-triF-Et)amine; n-BuLi / tetrahydrofuran; hexane / 1 h
5.2: Me3SiCl / 0.58 h / -78 - 0 °C
6.1: 0.310 g / LiAlH4 / tetrahydrofuran / 5 h / Heating
7.1: n-Bu2SnO / toluene / 0.75 h / Heating
7.2: 71 percent / CH2Cl2 / 1 h / 0 °C
With
dmap; lithium hydroxide; lithium aluminium tetrahydride; n-butyllithium; hydrogen; dihydrogen peroxide; sodium hexamethyldisilazane; di(n-butyl)tin oxide; potassium carbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; hexane; N,N-dimethyl-formamide; toluene;
5.1: Ireland-Claisen rearrngement;
DOI:10.1016/j.tetlet.2007.07.182
