5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin

Base Information

• Chemical Name: 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin
• CAS No.: 1612861-20-7
• Molecular Formula: C₅₀H₄₀N₄O₃
• Molecular Weight: 744.893
• Mol file: 1612861-20-7.mol

Synonyms:5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin

Chemical Property of 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin

There total 2 articles about 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

5-(4’-hydroxyphenyl)-10,15,20-triphenylporphyrin + 5-bromovaleric acid methyl ester (5454-83-1) → 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin (1612861-20-7)

Guidance literature:

5-(4’-hydroxyphenyl)-10,15,20-triphenylporphyrin; With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 0.25h;

5-bromovaleric acid methyl ester; In N,N-dimethyl-formamide; at 60 ℃; for 4h;

DOI:10.1016/j.tet.2014.05.007

Reference yield:

5-(4-acetoxyphenyl)-10,15,20-triphenylporphyrin (1380091-43-9) → 5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin (1612861-20-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium methylate / tetrahydrofuran; methanol / 6 h / Reflux

2.1: potassium carbonate; 18-crown-6 ether / N,N-dimethyl-formamide / 0.25 h / 60 °C

2.2: 4 h / 60 °C

With 18-crown-6 ether; sodium methylate; potassium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; 2.2: |Williamson Ether Synthesis;

DOI:10.1016/j.tet.2014.05.007

Reference yield: 80.0%

5-(4-(4-methoxycarbonylbutyloxy)phenyl)-10,15,20-triphenylporphyrin (1612861-20-7) + methylmagnesium bromide (75-16-1) → 5-(4-(5-hydroxy-5,5-dimethylpentyloxy)phenyl)-10,15,20-triphenylporphyrin (1612861-16-1)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2014.05.007

upstream raw materials:

5-(4-acetoxyphenyl)-10,15,20-triphenylporphyrin

5-bromovaleric acid methyl ester

Downstream raw materials:

5-(4-(5-hydroxy-5,5-dimethylpentyloxy)phenyl)-10,15,20-triphenylporphyrin