5-PREGNENE-3B,17A,20B-TRIOL

Base Information

• Chemical Name: 5-PREGNENE-3B,17A,20B-TRIOL
• CAS No.: 2204-13-9
• Molecular Formula: C21H34 O3
• Molecular Weight: 334.499
• Mol file: 2204-13-9.mol

Synonyms:Pregn-5-ene-3b,17,20b-triol (7CI,8CI); 3b,17a,20b-Trihydroxypregn-5-ene

Chemical Property of 5-PREGNENE-3B,17A,20B-TRIOL

Chemical Property:

• Refractive Index: 1.563
• PSA: 60.69000
• LogP: 3.42200

Purity/Quality:

99% ^*data from raw suppliers

(3-BETA,20R)-PREGN-5-ENE-3,17,20-TRIOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (3β,20R)-Pregn-5-ene-3,17,20-triol is a steroid metabolite of Pregnenolone (P712200).

Technology Process of 5-PREGNENE-3B,17A,20B-TRIOL

There total 12 articles about 5-PREGNENE-3B,17A,20B-TRIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (20S)-17βH-pregnene-(5)-triol-(3β,17,20) (903-67-3,2204-13-9,29599-45-9,59042-35-2)

Guidance literature:

With osmium(VIII) oxide; diethyl ether; at 20 ℃; Kochen des Reaktionsprodukts in Aethanol mit wss. Na₂SO₃;

Reference yield:

17α-hydroxy-3β,21-diacetoxy-5-pregnen-20-one (3517-42-8) → Δ5-pregnene-3β,17α,20α-triol (903-67-3) + Δ5-pregnene-3β,17α,20S-triol (2204-13-9)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In diethylene glycol;

Reference yield:

3β-acetoxy-17α-hydroxy-5-pregnen-20-one (1863-39-4) → Δ5-pregnene-3β,17α,20α-triol (903-67-3) + Δ5-pregnene-3β,17α,20S-triol (2204-13-9)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

upstream raw materials:

3β-acetoxy-17α-hydroxy-5-pregnen-20-one

17α-hydroxy-3β,21-diacetoxy-5-pregnen-20-one

3β,20β_F-diacetoxy-16α,17-epoxy-pregn-5-ene

diethyl ether

Downstream raw materials:

dehydroepiandrosterone

Progesterone

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