2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

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Chemical Name:2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate
CAS No.:1384271-41-3
Molecular Formula:C₁₇H₁₁N₇O₄
Molecular Weight:377.319
Hs Code.:

Synonyms:2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

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Chemical Property of 2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

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Technology Process of 2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

There total 3 articles about 2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 1234687-35-4
4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoic acid

: 1384271-41-3
2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

Guidance literature:: With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dimethyl sulfoxide; at 40 ℃; for 2h;
DOI:10.1002/chem.201200382

Reference yield:

: 14080-23-0
2-cyanopyrimidine

: 1384271-41-3
2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / 9 h / Reflux

1.2: 20 °C

2.1: pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 2 h / 40 °C

With pyridine; hydrazine hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dimethyl sulfoxide;
DOI:10.1002/chem.201200382

Reference yield:

: 619-65-8,333406-09-0
4-cyanobenzoic Acid

: 1384271-41-3
2,5-dioxopyrrolidin-1-yl 4-(6-(pyrimidin-2-yl)-1,2,4,5-tetrazin-3-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / 9 h / Reflux

1.2: 20 °C

2.1: pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dimethyl sulfoxide / 2 h / 40 °C

With pyridine; hydrazine hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; dimethyl sulfoxide;
DOI:10.1002/chem.201200382