4,6-Dimethoxyindoline-2,3-dione

Base Information

Chemical Name:4,6-Dimethoxyindoline-2,3-dione
CAS No.:21544-81-0
Molecular Formula:C10H9 N O4
Molecular Weight:207.186
Hs Code.:2933990090
European Community (EC) Number:874-201-4
DSSTox Substance ID:DTXSID30468533
Wikidata:Q72467905
Mol file:21544-81-0.mol

Synonyms:4,6-Dimethoxyindoline-2,3-dione;21544-81-0;4,6-dimethoxy-1H-indole-2,3-dione;4,6-Dimethoxyisatin;4,6-dimethoxy-2,3-dihydro-1H-indole-2,3-dione;MFCD09031988;1H-Indole-2,3-dione, 4,6-dimethoxy-;4,6-dimethoxy-2,3-dioxoindoline;SCHEMBL347461;4,6-dimethoxyindole-2,3-dione;DTXSID30468533;FAMGTYWNHVETJC-UHFFFAOYSA-N;AMY13969;AKOS000150100;SB66131;AC-20706;DS-11471;SY107652;BB 0262485;CS-0042851;FT-0715381;EN300-44245;4 pound not6-Dimethoxyindoline-2 pound not3-dione;A850201;Z247609734

Suppliers and Price of 4,6-Dimethoxyindoline-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
4,6-Dimethoxy-1H-indole-2,3-dione 95%
10 g
$ 535.00

SynChem
4,6-Dimethoxy-1H-indole-2,3-dione 95%
5 g
$ 391.00

SynChem
4,6-Dimethoxy-1H-indole-2,3-dione 95%
1 g
$ 98.00

Matrix Scientific
4,6-Dimethoxy-1H-indole-2,3-dione
500mg
$ 394.00

Crysdot
4,6-Dimethoxyindoline-2,3-dione 98%
5g
$ 266.00

Chemenu
4,6-Dimethoxy-1H-indole-2,3-dione 95%+
5g
$ 316.00

Chemenu
4,6-Dimethoxy-1H-indole-2,3-dione 95%+
10g
$ 526.00

Biosynth Carbosynth
4,6-Dimethoxy-1H-indole-2,3-dione
500 mg
$ 250.00

Biosynth Carbosynth
4,6-Dimethoxy-1H-indole-2,3-dione
100 mg
$ 72.00

Biosynth Carbosynth
4,6-Dimethoxy-1H-indole-2,3-dione
250 mg
$ 145.00

Total 33 raw suppliers

Chemical Property of 4,6-Dimethoxyindoline-2,3-dione

Chemical Property:

Melting Point:300-304℃
Refractive Index:1.567
PKA:8.65±0.20(Predicted)
PSA：64.63000
Density:1.331
LogP:0.97660
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:207.05315777
Heavy Atom Count:15
Complexity:291

Purity/Quality:

98% ^*data from raw suppliers

4,6-Dimethoxy-1H-indole-2,3-dione 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C(=C1)OC)C(=O)C(=O)N2

Technology Process of 4,6-Dimethoxyindoline-2,3-dione

There total 5 articles about 4,6-Dimethoxyindoline-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 79-37-8
oxalyl dichloride

: 40891-33-6
3,5-dimethoxyaniline hydrochloride

: 21544-81-0
4,6-dimethoxyindoline-2,3-dione

Guidance literature:: at 165 ℃; for 0.5h;
DOI:10.1021/jm0509389

Reference yield: 80.0%

: 79-37-8
oxalyl dichloride

: 10272-07-8
3.5-dimethoxyaniline

: 21544-81-0
4,6-dimethoxyindoline-2,3-dione

Guidance literature:: at 165 ℃; for 0.5h;
DOI:10.1016/j.tet.2017.12.053

Reference yield:

: 10272-07-8
3.5-dimethoxyaniline

: 21544-81-0
4,6-dimethoxyindoline-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / diethyl ether / 1.5 h / 0 - 10 °C

2: diethyl ether / 2 h / 170 °C

With hydrogenchloride; In diethyl ether;