2-Methyl-1-naphthylmagnesium bromide

Base Information

• Chemical Name: 2-Methyl-1-naphthylmagnesium bromide
• CAS No.: 21450-90-8
• Molecular Formula: C11H9BrMg
• Molecular Weight: 245.401
• Hs Code.: 29310099
• European Community (EC) Number: 806-300-5
• Mol file: 21450-90-8.mol

Synonyms:2-Methyl-1-naphthylmagnesium bromide;21450-90-8;magnesium;2-methyl-1H-naphthalen-1-ide;bromide;MFCD01311486;2-Methyl-1-naphthylmagnesium bromide, 0.25 M in THF;2-Methyl-1-naphthylmagnesium bromide, 0.25 M in 2-MeTHF;2-Methyl-1-naphthylmagnesium bromide 0.25 M in Tetrahydrofuran;Magnesium,bromo(2-methyl-1-naphthalenyl)-;SCHEMBL1142592;FRKJGFAPMOHVAM-UHFFFAOYSA-M;2-methyl-1-naphthyl magnesium bromide;AKOS016017713

Chemical Property of 2-Methyl-1-naphthylmagnesium bromide

Chemical Property:

• Boiling Point: 65 °C(lit.)
• Flash Point: 1 °F
• PSA: 0.00000
• Density: 0.921 g/mL at 25 °C(lit.)
• LogP: 3.79400
• Storage Temp.: 2-8°C
• Sensitive.: Air & Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 243.97380
• Heavy Atom Count: 13
• Complexity: 208

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methyl-1-naphthylmagnesium bromide 0.25 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F;C
• Hazard Codes: F,C,Xn
• Statements: 11-14-19-22-34-40-36/37/38
• Safety Statements: 16-26-33-36/37/39-45-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=[C-]C2=CC=CC=C2C=C1.[Mg+2].[Br-]

Technology Process of 2-Methyl-1-naphthylmagnesium bromide

There total 1 articles about 2-Methyl-1-naphthylmagnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-2-methylnaphtalene (2586-62-1) → (2-methyl-1-naphthyl)magnesium bromide (21450-90-8)

Guidance literature:

With magnesium; In diethyl ether; for 2h; Heating; ultrasonic heating;

DOI:10.1246/bcsj.59.2044

Reference yield: 96.0%

2,4,6-trimethylphenyl bromide (576-83-0) + (2-methyl-1-naphthyl)magnesium bromide (21450-90-8) → 2-methyl-1-(2',4',6'-trimethylphenyl)naphthalene

Guidance literature:

With [Pd(μ-Cl)Cl(N,N′-bis(2,6-bis(diphenylmethyl)-4-methylphenyl)imidazol-2-ylidene)]₂; In 1,4-dioxane; at 60 ℃; for 16h; Inert atmosphere; Glovebox;

DOI:10.1039/c4ob01269k

Reference yield: 94.0%

(Z)-1,2-diphenylvinyl dimethylcarbamate (1208405-05-3) + (2-methyl-1-naphthyl)magnesium bromide (21450-90-8) → (Z)-1-(1,2-diphenylvinyl)-2-methylnaphthalene

Guidance literature:

With N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene hydrochloride; palladium diacetate; In tetrahydrofuran; at 50 ℃; for 3h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c01127

upstream raw materials:

1-bromo-2-methylnaphtalene

Downstream raw materials:

Dibenzo[c,mno]chrysene

(2-methyl-[1]naphthyl)-[2]naphthyl ketone

(R)-2,2'-dimethyl-1,1'-binaphthyl

(S)-(+)-2,2'-dimethyl-1,1'-binaphthyl