allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Base Information

Chemical Name:allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside
CAS No.:245110-01-4
Molecular Formula:C₄₆H₆₁N₃O₁₁Si
Molecular Weight:860.089
Hs Code.:

Synonyms:allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Suppliers and Price of allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

There total 3 articles about allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 245110-00-3
2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosyl trichloroacetimidate

: allyl 2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

: 245110-01-4
allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Guidance literature:: With t-butyldimethylsiyl triflate; In dichloromethane; toluene; at -20 ℃; for 1.5h;
DOI:10.1016/S0040-4020(99)00526-8

Reference yield:

: 138688-77-4
(2R,4aR,7R,8R,8aS)-7-azido-8-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-6-ol

: 245110-01-4
allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / CH₂Cl₂ / 5 h

2: 84 percent / tert-butyldimethylsilyl triflate / toluene; CH₂Cl₂ / 1.5 h / -20 °C

With t-butyldimethylsiyl triflate; potassium carbonate; In dichloromethane; toluene; 1: Addition / 2: Condensation;
DOI:10.1016/S0040-4020(99)00526-8

Reference yield:

: thexyldimethylsilyl 2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside

: 245110-01-4
allyl (2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-(1->4)-2-O-acetyl-3-O-benzyl-6-O-thexyldimethylsilyl-α-L-idopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: Bu₄NF; AcOH / tetrahydrofuran / 4 h / -40 °C

2: K₂CO₃ / CH₂Cl₂ / 5 h

3: 84 percent / tert-butyldimethylsilyl triflate / toluene; CH₂Cl₂ / 1.5 h / -20 °C

With t-butyldimethylsiyl triflate; tetrabutyl ammonium fluoride; potassium carbonate; acetic acid; In tetrahydrofuran; dichloromethane; toluene; 1: desilylation / 2: Addition / 3: Condensation;
DOI:10.1016/S0040-4020(99)00526-8