2-CHLORO-4-(4-CHLOROPHENYL)THIAZOLE

Base Information

• Chemical Name: 2-CHLORO-4-(4-CHLOROPHENYL)THIAZOLE
• CAS No.: 2103-96-0
• Molecular Formula: C9H5 Cl2 N S
• Molecular Weight: 230.117
• Hs Code.: 2934100090
• Mol file: 2103-96-0.mol

Synonyms:Thiazole,2-chloro-4-(p-chlorophenyl)- (7CI,8CI); 2-Chloro-4-(p-chlorophenyl)thiazole

Chemical Property of 2-CHLORO-4-(4-CHLOROPHENYL)THIAZOLE

Chemical Property:

• Melting Point: 97-101 °C
• PSA: 41.13000
• LogP: 4.11690

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-4-(4-chlorophenyl)thiazole ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-37/38-41
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-4-(4-CHLOROPHENYL)THIAZOLE

There total 2 articles about 2-CHLORO-4-(4-CHLOROPHENYL)THIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-chloro-phenyl)-2-thiocyanato-ethanone (19339-59-4) → 2-chloro-4-(4-chlorophenyl)thiazole (2103-96-0)

Guidance literature:

With hydrogenchloride; diethyl ether;

Reference yield:

→ 2-chloro-4-(4-chlorophenyl)thiazole (2103-96-0)

Guidance literature:

4-Chlorphenacylthiocyanat , HCl (Suspension in Et2O);

Reference yield: 94.0%

2-chloro-4-(4-chlorophenyl)thiazole (2103-96-0) + methylamine (74-89-5) → 4-(4-chlorophenyl)-N-methylthiazol-2-amine (21344-78-5)

Guidance literature:

With copper(l) iodide; potassium carbonate; In dimethyl sulfoxide; at 100 ℃; for 3h; Temperature; Microwave irradiation; Green chemistry;

DOI:10.1002/adsc.201300591

upstream raw materials:

1-(4-chloro-phenyl)-2-thiocyanato-ethanone

Downstream raw materials:

3-(4-chloro-phenyl)-5H-thiazolo[2,3-b]quinazoline

4-[4-(4-chloro-phenyl)-thiazol-2-ylamino]-2-imino-3-phenyl-2,3-dihydro-thiazole-5-carboxylic acid ethyl ester

{4-[4-(4-chloro-phenyl)-thiazol-2-ylamino]-phenyl}-acetic acid

3-(4-chloro-phenyl)-benzo[g]thiazolo[2,3-b]quinazolin-5-one

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