(2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide

Base Information

Chemical Name:(2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide
CAS No.:90293-10-0
Molecular Formula:C₈H₉O₃PS
Molecular Weight:216.197
Hs Code.:
DSSTox Substance ID:DTXSID601338854

Synonyms:90293-10-0;(2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide;DTXSID601338854

Suppliers and Price of (2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide

Chemical Property:

Boiling Point:274.4°Cat760mmHg
Flash Point:119.8°C
PSA：69.59000
Density:1.37g/cm³
LogP:3.11710
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:216.00100232
Heavy Atom Count:13
Complexity:233

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP1(=S)OCC2=CC=CC=C2O1
Isomeric SMILES:CO[P@]1(=S)OCC2=CC=CC=C2O1

Technology Process of (2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide

There total 7 articles about (2S)-2-Methoxy-4H-1,3,2-benzodioxaphosphorin 2-sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 67-56-1
methanol

: 121904-24-3
(S)_C(R)_P-2-<1-(2-methoxycarbonylpyrrolidyl)>-4H-1,3,2-benzadioxaphosphorin 2-sulfide

: 90293-10-0
(S)-(-)-salithion

Guidance literature:: With sulfuric acid; 1.) reflux, 6 h, 2.) r.t., overnight;

Reference yield: 23.0%

: sodium 2-hydroxymethylphenoxide

: 96736-38-8
(R)-(-)-2,6-Dichloro-4-methylphenyl methyl phosphorochloridothionate

: 90293-10-0
(S)-(-)-salithion

Guidance literature:: With 15-crown-5; In chloroform; for 4h;

Reference yield:

: 67-56-1
methanol

: 1329994-63-9
2-[(4S)-4-isopropyloxazolidin-2-on-3-yl]-4H-1,3,2-benzodioxaphosphorin-2-sulfide

: 90293-10-0
(S)-(-)-salithion

: 90293-16-6
(R)-(+)-salithion

Guidance literature:: With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 12h; optical yield given as %ee; stereospecific reaction;
DOI:10.1002/ejoc.201100334