(2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene

Base Information

• Chemical Name: (2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene
• CAS No.: 85966-24-1
• Molecular Formula: C₂₁H₁₈O₅
• Molecular Weight: 350.371
• Mol file: 85966-24-1.mol

Synonyms:(2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene

Chemical Property of (2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene

There total 1 articles about (2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

(2R)-trans-2,3-dihydroxy-1-<(benzoyloxy)methyl>cyclohexa-4,6-diene (71481-04-4) + benzoyl chloride (98-88-4) → (2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene (85966-24-1) + (2R)-trans-2-(benzoyloxy)-1-<(benzoyloxy)methyl>-3-hydroxycyclohexa-4,6-diene (96247-05-1) + (2R)-trans-2,3-bis(benzoyloxy)-1-<(benzoyloxy)methyl>cyclohexa-4,6-diene (96247-04-0)

Guidance literature:

With pyridine; at -5 ℃;

DOI:10.1021/jo00213a030

Reference yield: 87.0%

(2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene (85966-24-1) → (+)-Pipoxide (29399-87-9)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; at 0 ℃; for 1h;

DOI:10.1021/jo00213a030

Reference yield: 64.0%

(2R)-trans-3-(benzoyloxy)-1-<(benzoyloxy)methyl>-2-hydroxycyclohexa-4,6-diene (85966-24-1) + acetyl chloride (75-36-5) → (2R)-trans-2-acetoxy-3-(benzoyloxy)-1-<(benzoyloxy)methyl>cyclohexa-4,6-diene (86702-29-6) + C21H16O4 (106262-10-6)

Guidance literature:

With triethylamine; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1016/S0040-4039(00)81832-8

upstream raw materials:

(2R)-trans-2,3-dihydroxy-1-<(benzoyloxy)methyl>cyclohexa-4,6-diene

benzoyl chloride

Downstream raw materials:

(+)-Pipoxide

(2R)-trans-2-acetoxy-3-(benzoyloxy)-1-<(benzoyloxy)methyl>cyclohexa-4,6-diene

C₂₁H₁₆O₄

Pipoxide acetate