Benzene, 1-(1-butynyl)-4-methoxy- (9CI)

Base Information

• Chemical Name: Benzene, 1-(1-butynyl)-4-methoxy- (9CI)
• CAS No.: 197250-99-0
• Molecular Formula: C11H12 O
• Molecular Weight: 160.216
• Mol file: 197250-99-0.mol

Synonyms:Benzene,1-(1-butynyl)-4-methoxy- (9CI); 1-(4-Methoxyphenyl)-1-butyne

Chemical Property of Benzene, 1-(1-butynyl)-4-methoxy- (9CI)

Chemical Property:

• PSA: 9.23000
• LogP: 2.45670

Purity/Quality:

1-(But-1-yn-1-yl)-4-methoxybenzene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-(1-butynyl)-4-methoxy- (9CI)

There total 13 articles about Benzene, 1-(1-butynyl)-4-methoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

pent-2-ynoic acid (5963-77-9) + 4-chloromethoxybenzene (623-12-1) → 1-(but-1-yn-1-yl)-4-methoxybenzene (197250-99-0)

Guidance literature:

With bis[dicyclohexyl(2,4,6-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane]palladium(II) dichloride; caesium carbonate; In tetrahydrofuran; at 80 ℃; for 24h;

DOI:10.1039/c6ra12916a

Reference yield: 94.0%

para-iodoanisole (696-62-8) + 1-butynyllithium (1119-18-2) → 1-(but-1-yn-1-yl)-4-methoxybenzene (197250-99-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; zinc dibromide; In tetrahydrofuran; at 60 ℃; for 4h;

DOI:10.1021/ja0379868

Reference yield: 89.0%

pent-2-ynoic acid (5963-77-9) + para-iodoanisole (696-62-8) → 1-(but-1-yn-1-yl)-4-methoxybenzene (197250-99-0)

Guidance literature:

With C₁₁H₂₀N₃⁽¹⁺⁾*C₂F₆NO₄S₂^(1-); palladium diacetate; at 60 - 65 ℃; for 6h; Inert atmosphere; Ionic liquid;

DOI:10.1002/ejoc.201900093

upstream raw materials:

para-iodoanisole

1-butynyllithium

hex-3-yne

4-methoxybenzonitrile

Downstream raw materials:

(2-{4-[(Z)-1-(4-Methoxy-phenyl)-2-phenyl-but-1-enyl]-phenoxy}-ethyl)-dimethyl-amine

(2-{4-[(E)-1-(4-Methoxy-phenyl)-2-phenyl-but-1-enyl]-phenoxy}-ethyl)-dimethyl-amine

4,4'-dimethoxydiphenylacetylene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 197250-99-0 Benzene, 1-(1-butynyl)-4-methoxy- (9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send