C₄₀H₃₁NO₈

Base Information

• Chemical Name: C₄₀H₃₁NO₈
• CAS No.: 1315503-87-7
• Molecular Formula: C₄₀H₃₁NO₈
• Molecular Weight: 653.688
• Mol file: 1315503-87-7.mol

Synonyms:C₄₀H₃₁NO₈

Chemical Property of C₄₀H₃₁NO₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₃₁NO₈

There total 18 articles about C₄₀H₃₁NO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C42H35NO9 (1315504-15-4) → C40H31NO8 (1315503-87-7)

Guidance literature:

With magnesium bromide diethyl etherate; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/ja205339p

Reference yield:

benzyl bromide (100-39-0) → C40H31NO8 (1315503-87-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 4 h / 20 °C

2: magnesium bromide diethyl etherate / tetrahydrofuran / 0 - 20 °C

With magnesium bromide diethyl etherate; potassium carbonate; In tetrahydrofuran; acetone;

DOI:10.1021/ja205339p

Reference yield:

C22H25NO4Si → C40H31NO8 (1315503-87-7)

Guidance literature:

Multi-step reaction with 10 steps

1.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 1 h / 20 °C

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.67 h / -78 °C

3.2: 0.08 h / 0 °C

4.1: borane-THF; (S)-Corey-Bakshi-Shibata oxazaborolidine / tetrahydrofuran; toluene / 2.5 h / -20 °C

5.1: ammonium cerium (IV) nitrate / water; acetonitrile / 0 °C

6.1: silver(l) oxide / dichloromethane / 18 h / 20 °C / Molecular sieve

7.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C

8.1: sodium ethanolate / ethanol / 18 h / 20 - 60 °C / Molecular sieve

9.1: potassium carbonate / acetone / 4 h / 20 °C

10.1: magnesium bromide diethyl etherate / tetrahydrofuran / 0 - 20 °C

With ammonium cerium (IV) nitrate; borane-THF; tetrabutyl ammonium fluoride; sodium ethanolate; magnesium bromide diethyl etherate; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; silver(l) oxide; lithium hexamethyldisilazane; (S)-Corey-Bakshi-Shibata oxazaborolidine; In tetrahydrofuran; ethanol; dichloromethane; water; acetone; toluene; acetonitrile;

DOI:10.1021/ja205339p

upstream raw materials:

7-(benzyloxy)-4-hydroxy-3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile

7-(benzyloxy)-4-(methoxymethoxy)-3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile

C₃₄H₄₀O₇Si

C₃₄H₄₀O₇Si