5,5-Diphenyl-pentanoic acid cyclohexylamide

Base Information

Chemical Name:5,5-Diphenyl-pentanoic acid cyclohexylamide
CAS No.:81311-70-8
Molecular Formula:C₂₃H₂₉NO
Molecular Weight:335.489
Hs Code.:

Synonyms:5,5-Diphenyl-pentanoic acid cyclohexylamide

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Chemical Property of 5,5-Diphenyl-pentanoic acid cyclohexylamide

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Technology Process of 5,5-Diphenyl-pentanoic acid cyclohexylamide

There total 4 articles about 5,5-Diphenyl-pentanoic acid cyclohexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 606-83-7
3,3-Diphenylpropionic acid

: 81311-70-8
5,5-Diphenyl-pentanoic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / BH₃*Me₂S / tetrahydrofuran / 48 h

2: butan-1-ol / 3 h / Heating

3: 50percent aq. KOH / butan-1-ol / 48 h / Heating

4: 200 °C

5: SOCl₂ / 3 h / 70 °C

6: Et₃N / benzene / 1 h

With potassium hydroxide; thionyl chloride; dimethylsulfide borane complex; triethylamine; In tetrahydrofuran; butan-1-ol; benzene;
DOI:10.1021/jm00348a019

Reference yield:

: 20017-67-8
3,3-diphenylpropan-1-ol

: 81311-70-8
5,5-Diphenyl-pentanoic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 5 steps

1: butan-1-ol / 3 h / Heating

2: 50percent aq. KOH / butan-1-ol / 48 h / Heating

3: 200 °C

4: SOCl₂ / 3 h / 70 °C

5: Et₃N / benzene / 1 h

With potassium hydroxide; thionyl chloride; triethylamine; In butan-1-ol; benzene;
DOI:10.1021/jm00348a019

Reference yield:

: 101790-37-8
2-(3,3-diphenylpropyl)malonic acid

: 81311-70-8
5,5-Diphenyl-pentanoic acid cyclohexylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 200 °C

2: SOCl₂ / 3 h / 70 °C

3: Et₃N / benzene / 1 h

With thionyl chloride; triethylamine; In benzene;
DOI:10.1021/jm00348a019