2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol

Base Information

• Chemical Name: 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol
• CAS No.: 186365-67-3
• Molecular Formula: C₁₃H₁₈Br₂O₅
• Molecular Weight: 414.091
• Mol file: 186365-67-3.mol

Synonyms:2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol

Chemical Property of 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol

There total 2 articles about 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-[2-(chloroethoxy)ethoxy]ethanol (5197-62-6) + 1,2-dibromo-4-hydroxy-5-methoxybenzene (38926-86-2) → 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol (186365-67-3)

Guidance literature:

With potassium carbonate; In acetonitrile; for 120h; Heating;

DOI:10.1039/cc9960002785

Reference yield:

2-methoxy-phenol (90-05-1) → 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol (186365-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / Br₂ / CH₂Cl₂ / -78 °C

2: 72 percent / K₂CO₃ / acetonitrile / 120 h / Heating

With bromine; potassium carbonate; In dichloromethane; acetonitrile;

DOI:10.1039/cc9960002785

Reference yield: 85.0%

p-toluenesulfonyl chloride (98-59-9) + 2-{2-[2-(4,5-Dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethanol (186365-67-3) → Toluene-4-sulfonic acid 2-{2-[2-(4,5-dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethyl ester (186365-70-8)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1039/cc9960002785

upstream raw materials:

2-[2-(chloroethoxy)ethoxy]ethanol

1,2-dibromo-4-hydroxy-5-methoxybenzene

2-methoxy-phenol

Downstream raw materials:

Toluene-4-sulfonic acid 2-{2-[2-(4,5-dibromo-2-methoxy-phenoxy)-ethoxy]-ethoxy}-ethyl ester

1,2-Dibromo-4-methoxy-5-(2-{2-[2-(4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenoxy)-ethoxy]-ethoxy}-ethoxy)-benzene

4-Methoxy-5-(2-{2-[2-(4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenoxy)-ethoxy]-ethoxy}-ethoxy)-phthalonitrile