4,5-dibromo-2-methoxyphenol

Base Information

• Chemical Name: 4,5-dibromo-2-methoxyphenol
• CAS No.: 38926-86-2
• Molecular Formula: C₇H₆Br₂O₂
• Molecular Weight: 281.931
• Mol file: 38926-86-2.mol

Synonyms:1,2-dibromo-4-hydroxy-5-methoxybenzene

Chemical Property of 4,5-dibromo-2-methoxyphenol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4,5-Dibromo-2-methoxy-phenol ＞97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dibromo-2-methoxyphenol

There total 10 articles about 4,5-dibromo-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-methoxy-phenol (90-05-1) → 1,2-dibromo-4-hydroxy-5-methoxybenzene (38926-86-2)

Guidance literature:

With bromine; In dichloromethane; at -78 ℃;

DOI:10.1039/cc9960002785

Reference yield: 42.0%

4,5-dibromobenzene-1,2-diol (2563-26-0) + methyl iodide (74-88-4) → 1,2-dibromo-4-hydroxy-5-methoxybenzene (38926-86-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 22h; Inert atmosphere;

DOI:10.1271/bbb.130199

Reference yield:

5-bromo-2-methoxyphenol (37942-01-1) → 1,2-dibromo-4-hydroxy-5-methoxybenzene (38926-86-2)

Guidance literature:

With bromine; acetic acid;

upstream raw materials:

2,3,4,5-tetrabromo-6-methoxyphenol

5-bromo-2-methoxyphenol

2-methoxy-phenol

2-methoxyphenyl acetate

Downstream raw materials:

4,5-dicyano-2-methoxyphenol

1-acetoxy-4,5-dibromo-2-methoxy-3-nitro-benzene

1-acetoxy-4-bromo-2-methoxy-5-nitro-benzene

1,2-dibromo-4,5-dimethoxy-3-nitrobenzene

Refernces

• 1、 Ariyoshi, Masaaki,Sugibayashi-Kajita, Makiko,Suzuki-Ichihara, Ayumi,Kato, Takayuki,Kamei, Tenpei,Itoh, Eiji,Ohta, Kazuchika. "Discotic liquid crystals of transition metal complexes 44:". . p. 1114 - 1123. Retrieved 2013/01/15.
• 2、 Kimura, Mutsumi,Misawa, Yoshinobu,Yamaguchi, Yuji,Hanabusa, Kenji,Shirai, Hirofusa. "Intra-complex electron transfer in a self-assembling phthalocyanine [2]pseudorotaxane". . p. 2785 - 2786. Retrieved 2007/10/03.