(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Base Information

Chemical Name:(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid
CAS No.:1380521-38-9
Molecular Formula:C₂₉H₃₆N₄O₁₀
Molecular Weight:600.626
Hs Code.:

Synonyms:(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Suppliers and Price of (8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

There total 6 articles about (8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1380521-30-1
(S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)-3-(2-(((tert-butoxy)carbonyl)amino)acetoxy)propanoic acid

: 1380521-38-9
(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / methanol / 4 h

2: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 12 h / 20 °C

With palladium on activated charcoal; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; water; acetonitrile;
DOI:10.1039/c2ob07050b

Reference yield:

: 860-55-9
(2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoyl)amino]-3-hydroxypropanoic acid

: 1380521-38-9
(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C

2: palladium on activated charcoal; hydrogen / methanol / 4 h

3: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 12 h / 20 °C

With palladium on activated charcoal; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; water; acetonitrile;
DOI:10.1039/c2ob07050b

Reference yield:

: 769922-77-2
(S)-benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate

: 1380521-38-9
(8S,11S)-8-benzyl-11-((2-(((tert-butoxy)carbonyl)amino)acetoxy)methyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / water; acetonitrile / 20 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 20 °C

3: palladium on activated charcoal; hydrogen / methanol / 4 h

4: N-ethyl-N,N-diisopropylamine / water; acetonitrile / 12 h / 20 °C

With palladium on activated charcoal; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; In methanol; water; acetonitrile;
DOI:10.1039/c2ob07050b