(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Base Information

Chemical Name:(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester
CAS No.:124322-03-8
Molecular Formula:C₄₆H₆₃N₅O₇
Molecular Weight:798.036
Hs Code.:

(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Synonyms:(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Suppliers and Price of (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

There total 5 articles about (S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30925-18-9
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

: 124322-03-8
(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂ / Ambient temperature

2: trifluoroacetic acid (TFA) / CH₂Cl₂ / 0.75 h / Ambient temperature

3: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂

With diethylphosphoryl cyanide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00167a009

Reference yield:

: 124322-00-5,146452-10-0
((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-cyclohexylmethyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-carbamic acid tert-butyl ester

: 124322-03-8
(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: HCl (gas) / diethyl ether / 0.25 h

2: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂ / Ambient temperature

3: trifluoroacetic acid (TFA) / CH₂Cl₂ / 0.75 h / Ambient temperature

4: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂

With hydrogenchloride; diethylphosphoryl cyanide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In diethyl ether; dichloromethane;
DOI:10.1021/jm00167a009

Reference yield:

: 136520-80-4
(2S,4S,5S)-5-Amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide; hydrochloride

: 124322-03-8
(S)-N-((1S,2S,4S)-1-Cyclohexylmethyl-2-hydroxy-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexyl)-2-phenylacetylamino-succinamic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂ / Ambient temperature

2: trifluoroacetic acid (TFA) / CH₂Cl₂ / 0.75 h / Ambient temperature

3: diisopropylethylamine, diethylphosphoryl cyanide (DEPC) / CH₂Cl₂

With diethylphosphoryl cyanide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jm00167a009