methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Base Information

Chemical Name:methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate
CAS No.:478701-10-9
Molecular Formula:C₄₇H₈₄O₉Si₄
Molecular Weight:905.521
Hs Code.:

Synonyms:methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Suppliers and Price of methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

There total 13 articles about methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 478701-16-5
methyl 2-(6'-O-benzyl-β-D-galactopyranosyloxy)-3-p-hydroxyphenyl propionate

: 478701-10-9
methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane;
DOI:10.1016/S0040-4039(02)01460-0

Reference yield:

: 290330-34-6
2,3,4-tri-O-acetyl-6-O-benzyl-α-D-galactopyranosyl bromide

: 478701-10-9
methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Guidance literature:: Multi-step reaction with 3 steps

1: AgOTf / molecular sieves 4 Angstroem / CH₂Cl₂ / 2 h / -30 - 20 °C

2: sodium methoxide / methanol / 7 h / 20 °C

3: 2,6-lutidine / CH₂Cl₂ / 1 h / 0 °C

With 2,6-dimethylpyridine; sodium methylate; silver trifluoromethanesulfonate; 4 A molecular sieve; In methanol; dichloromethane;
DOI:10.1016/j.tet.2005.06.022

Reference yield:

: 481072-51-9
methyl 3-p-hydroxyphenyl-2-t-butyldimethylsiloxy propionate

: 478701-10-9
methyl 2-(6'-O-benzyl-2',3',4'-tri-O-t-butyldimethylsilyl-β-D-galactopyranosyloxy)-3-p-t-butyldimethylsiloxyphenyl propionate

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / pyridine

2: 98 percent / tetra-n-butylammonium fluoride; acetic acid / tetrahydrofuran

3: AgOTf / molecular sieves 4 Angstroem / CH₂Cl₂ / 2 h / -30 - 20 °C

4: sodium methoxide / methanol / 7 h / 20 °C

5: 2,6-lutidine / CH₂Cl₂ / 1 h / 0 °C

With pyridine; 2,6-dimethylpyridine; tetrabutyl ammonium fluoride; sodium methylate; silver trifluoromethanesulfonate; acetic acid; 4 A molecular sieve; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tet.2005.06.022