2-Fluoro-1-(4-fluorophenyl)ethanamine

Base Information

Chemical Name:2-Fluoro-1-(4-fluorophenyl)ethanamine
CAS No.:929972-16-7
Molecular Formula:C₈H₉F₂N
Molecular Weight:157.163
Hs Code.:
ChEMBL ID:CHEMBL4555809
DSSTox Substance ID:DTXSID801260217
Nikkaji Number:J2.867.639E

Synonyms:2-fluoro-1-(4-fluorophenyl)ethanamine;929972-16-7;2-fluoro-1-(4-fluorophenyl)ethan-1-amine;CHEMBL4555809;SCHEMBL14463941;DTXSID801260217;EN300-87185;N14614;2-Fluoro-1-(4-fluorophenyl)ethylamine, AldrichCPR

Suppliers and Price of 2-Fluoro-1-(4-fluorophenyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Fluoro-1-(4-fluorophenyl)ethanamine

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:157.07030562
Heavy Atom Count:11
Complexity:111

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CF)N)F

Technology Process of 2-Fluoro-1-(4-fluorophenyl)ethanamine

There total 3 articles about 2-Fluoro-1-(4-fluorophenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₈H₇F₂N

: 929972-16-7
2-fluoro-1-(4-fluorophenyl)ethylamine

Guidance literature:: C₈H₇F₂N; With sodium tetrahydroborate; In ethanol; at 20 ℃; for 24h; Inert atmosphere;

With hydrogenchloride; In ethanol; water;

With sodium hydroxide; In ethanol; water;
DOI:10.1016/j.tet.2010.06.081

Reference yield:

: 369-41-5
2-fluoro-1-(4-fluorophenyl)ethanone

: 929972-16-7
2-fluoro-1-(4-fluorophenyl)ethylamine

Guidance literature:: With ammonium acetate; sodium cyanoborohydride; In methanol; at 20 ℃; for 24h;
DOI:10.1002/anie.201510554

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 929972-16-7
2-fluoro-1-(4-fluorophenyl)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium fluoride; zinc(II) fluoride / acetonitrile / 24 h / 100 °C

2: ammonium acetate; sodium cyanoborohydride / methanol / 24 h / 20 °C

With potassium fluoride; zinc(II) fluoride; ammonium acetate; sodium cyanoborohydride; In methanol; acetonitrile;
DOI:10.1002/anie.201510554