2-((R)-2,2-Diphenylcyclopentoxy)ethanal

Base Information

• Chemical Name: 2-((R)-2,2-Diphenylcyclopentoxy)ethanal
• CAS No.: 156908-41-7
• Molecular Formula: C₁₉H₂₀O₂
• Molecular Weight: 280.367
• Mol file: 156908-41-7.mol

Synonyms:2-((R)-2,2-Diphenylcyclopentoxy)ethanal

Chemical Property of 2-((R)-2,2-Diphenylcyclopentoxy)ethanal

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-((R)-2,2-Diphenylcyclopentoxy)ethanal

There total 2 articles about 2-((R)-2,2-Diphenylcyclopentoxy)ethanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-(-)-2,2-diphenylcyclopentanol (126421-67-8) → 2-((R)-2,2-Diphenylcyclopentoxy)ethanal (156908-41-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / KH / tetrahydrofuran / 1.) 20 deg C, 1 h, 2.) r.t., 1 h

2: 1.) O₃, 2.) Zn, 50percent AcOH / 1.) CH₂Cl₂, -78 deg C, 2.) 0 deg C, 30 min; r.t., 2 h

With potassium hydride; ozone; acetic acid; zinc; In tetrahydrofuran;

DOI:10.1021/jo00095a038

Reference yield:

3-((R)-2,2-Diphenylcyclopentoxy)-1-propene (156908-40-6) → 2-((R)-2,2-Diphenylcyclopentoxy)ethanal (156908-41-7)

Guidance literature:

With ozone; acetic acid; zinc; Yield given. Multistep reaction; 1.) CH₂Cl₂, -78 deg C, 2.) 0 deg C, 30 min; r.t., 2 h;

DOI:10.1021/jo00095a038

Reference yield: 99.0%

chloro-trimethyl-silane (75-77-4) + 2-((R)-2,2-Diphenylcyclopentoxy)ethanal (156908-41-7) → 2-[[(R)-(2,2-diphenylcyclopentyl)oxy]etheneyloxy]trimethylsilane

Guidance literature:

With triethylamine; In acetonitrile; at 81 ℃;

DOI:10.1021/ol9909886

upstream raw materials:

3-((R)-2,2-Diphenylcyclopentoxy)-1-propene

(R)-(-)-2,2-diphenylcyclopentanol

Downstream raw materials:

2-[(R)-(2,2-diphenylcyclopentyl)oxy]-(Z)-ethenol benzoate

Refernces