(S)-2-AMINO-7-HYDROXYTETRALIN HYDROBROMIDE

Base Information

• Chemical Name: (S)-2-AMINO-7-HYDROXYTETRALIN HYDROBROMIDE
• CAS No.: 194785-79-0
• Molecular Formula: BrH*C₁₀H₁₃NO
• Molecular Weight: 244.131
• Mol file: 194785-79-0.mol

Synonyms:2-Naphthalenol,7-amino-5,6,7,8-tetrahydro-, hydrobromide, (7S)- (9CI); 2-Naphthalenol,7-amino-5,6,7,8-tetrahydro-, hydrobromide, (S)-;(2S)-2-Amino-7-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide;(S)-2-Amino-7-hydroxytetralin hydrobromide

Chemical Property of (S)-2-AMINO-7-HYDROXYTETRALIN HYDROBROMIDE

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-AMINO-7-HYDROXYTETRALIN HYDROBROMIDE

There total 19 articles about (S)-2-AMINO-7-HYDROXYTETRALIN HYDROBROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene (4003-89-8,118298-16-1) → 7-hydroxy-1,2,3,4-tetrahydro-2-naphthylamine hydrobromide (194785-79-0)

Guidance literature:

With hydrogen bromide; acetic acid; In water; toluene; at 110 ℃;

Reference yield: 99.0%

(2R)-7-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine (121216-43-1,118298-16-1) → (7R)-7-amino-5,6,7,8-tetrahydronaphthalen-2-ol hydrobromide (220640-10-8,194785-79-0)

Guidance literature:

With hydrogen bromide; In water; Reflux;

Reference yield: 99.0%

(2S)-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine hydrochloride (158223-16-6) → (7S)-7-amino-5,6,7,8-tetrahydronaphthalen-2-ol hydrobromide (194785-79-0)

Guidance literature:

(2S)-7-methoxy-1,2,3,4-tetrahydro-2-naphthylamine hydrochloride; With sodium hydroxide;

With hydrogen bromide; for 4h; Heating;

DOI:10.1248/cpb.49.1018

upstream raw materials:

2-amino-7-methoxy-1,2,3,4-tetrahydronaphthalene

7-Methoxy-1,2,3,4-tetrahydro-(2R)-2-naphthaleneamine hydrochloride

7-methoxyl-2-tetralone

7-methoxy-3,4-dihydro-1H-naphthalen-2-one oxime

Downstream raw materials:

N-[(2S)-7-((2-[(cyclopropylcarbonyl)amino]pyridin-4-yl)oxy)-1,2,3,4-tetrahydronaphthalen-2-yl]-3-[(dimethylamino)methyl]-5-(trifluoromethyl)benzamide hydrochloride

(-)-2-[(2S)-2-[[(2R)-2-[4-Benzyloxy-3-(2-benzyloxyethyl)-phenyl]-2-hydroxyethyl]amino]-1,2,3,4-tetrahydronaphthalen-7-yloxy]-N,N-dimethylacetamide

(-)-(1R)-1-[4-benzyloxy-3-(2-benzyloxyethyl)phenyl]-2-((2S)-7-hydroxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)ethanol

(-)-(2R)-2-[4-benzyloxy-3-(2-benzyloxyethyl)phenyl]-2-hydroxy-N-((2S)-7-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide